Applying multidimensional computerized adaptive testing to the MSQOL-54: a simulation study. [PDF]
Giordano A +23 more
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Computerized adaptive testing for assessing substance use and substance use disorder: A systematic review. [PDF]
Boness CL +5 more
europepmc +1 more source
Developing Computerized Adaptive Testing for a National Health Professionals Exam: An Attempt from Psychometric Simulations. [PDF]
Xu L, Jiang Z, Han Y, Liang H, Ouyang J.
europepmc +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
A Likelihood-Based Profile Shrinkage Algorithm for Efficient Cognitive Diagnostic Computerized Adaptive Testing (CD-CAT). [PDF]
Tang X, Cheng Y.
europepmc +1 more source
Feasibility of PROMIS using computerized adaptive testing during inpatient rehabilitation. [PDF]
Rafiq RB +6 more
europepmc +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Cognitive Diagnosis Computerized Adaptive Testing (CD-CAT) for Adolescent Internet Gaming Disorder: A Conceptual Assessment Framework. [PDF]
Jia M, Liu J.
europepmc +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source

