Results 81 to 90 of about 56,434 (298)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Optimal Unviersal Schedules for Discrete Broadcast [PDF]

open access: yes, 2004
In this paper we study the scenario in which a server sends dynamic data over a single broadcast channel to a number of passive clients. We consider the data to consist of discrete packets, where each update is sent in a separate packet.
Bruck, Jehoshua   +2 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

An Adaptive Strategy for Active Learning with Smooth Decision Boundary

open access: yes, 2017
We present the first adaptive strategy for active learning in the setting of classification with smooth decision boundary. The problem of adaptivity (to unknown distributional parameters) has remained opened since the seminal work of Castro and Nowak ...
Carpentier, Alexandra   +2 more
core  

Adaptive Wireless Networking [PDF]

open access: yes, 2003
This paper presents the Adaptive Wireless Networking (AWGN) project. The project aims to develop methods and technologies that can be used to design efficient adaptable and reconfigurable mobile terminals for future wireless communication systems.
Hoeksema, Fokke   +3 more
core   +1 more source

Adaptive Ensemble Biomolecular Simulations at Scale

open access: yes, 2019
Recent advances in both theory and methods have created opportunities to simulate biomolecular processes more efficiently using adaptive ensemble simulations.
Balasubramanian, Vivek   +5 more
core   +1 more source

How Adaptive Is an Adaptive Test: Are All Adaptive Tests Adaptive?

open access: yesJournal of Computerized Adaptive Testing, 2019
The primary distinguishing feature of computerized adaptive testing (CAT) is that sets of items that are administered to examinees are specifically selected for each examinee during the test process. This implies that examinees who respond differently to items on a test will get different sets of test items.
Mark Reckase, Unhee Ju, Sewon Kim
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A finite-element toolbox for the stationary Gross-Pitaevskii equation with rotation

open access: yes, 2016
We present a new numerical system using classical finite elements with mesh adaptivity for computing stationary solutions of the Gross-Pitaevskii equation.
Auliac, Sylvain   +3 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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