Results 161 to 170 of about 34,023 (303)

Enhancing early Alzheimer's disease clinical trials through prognostic score covariate adjustment. [PDF]

Alzheimers Dement
Scodari BT, Brown R, Jiang X, Shen C, Ferber K, Wu S, Gao F, Bullain S, Millen B.   +8 more
europepmc   +1 more source

Beyond statistical significance: Interpreting effect sizes in dental research

Journal of Periodontology, EarlyView.
Despite substantial advances in dental and periodontal research, study findings are still frequently interpreted primarily on the basis of statistical significance, potentially leading to overestimation of their clinical relevance. This issue is particularly relevant in studies, where small absolute numerical changes in outcomes such as clinical ...
Dimitris Sokos, Lotte P. M. Weijdijk, Dagmar Else Slot, G. A van der Weijden   +3 more
wiley   +1 more source

Baseline MRI markers and clinical outcomes during anti-amyloid β therapy: A real-world study in a Japanese dementia center. [PDF]

J Prev Alzheimers Dis
Kujuro Y, Saito M, Maruko M, Kamiyama K, Nakano A, Qian E, Okamura T, Ito D, Kageyama T, Sugiyama I, Ishihara E, Kuwahara T, Moritani K, Katai H, Hattori H.   +14 more
europepmc   +1 more source

Dual biologic therapy in inflammatory bowel disease, a retrospective cohort study of vedolizumab and anti‐tumor necrosis factor alpha therapy in children

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite advances in pediatric inflammatory bowel disease (PIBD) with biologics, remission rates remain at 47%–60% with loss‐of‐response rates at 60%–68%. Evidence for efficacy of dual biologic therapy (DBT) with anti‐tumor necrosis factor alpha therapy (anti‐TNF‐α)‐ vedolizumab (VDZ) for children refractory to anti‐TNF‐α therapy is ...
Jonathan E. M. O'Donnell, Carlie Bolles, Claire R. Reilly, Manal Morgan, Christopher Burgess, Fariha Balouch, Peter J. Lewindon   +6 more
wiley   +1 more source

Longitudinal associations of serum MCP-1 with cognitive decline and psychological stress in biomarker-confirmed Alzheimer's disease: A pilot study. [PDF]

Brain Behav Immun Health
Yasuno F, Kimura Y, Yamauchi Y, Minami H, Kasuga K, Ikeuchi T, Takeda A, Sakurai T.   +7 more
europepmc   +1 more source

Artificial Intelligence Revolution: The Need for a Regulatory and Governance Framework in Dentistry

Journal of Dental Education, EarlyView.
Ehsan Jozaghi
wiley   +1 more source

Fecal microRNA signatures as non‐invasive diagnostic and prognostic markers of pediatric inflammatory bowel diseases

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives The identification of novel noninvasive diagnostic and prognostic biomarkers for pediatric inflammatory bowel disease (PIBD), including pediatric Crohn's disease (pCD) and ulcerative colitis (pUC), is crucial for improving therapeutic outcomes.
Tereza Pinkasova, Tereza Deissova, Matej Hrunka, Martina Ambrozova, Dagmar Al Tukmachi, Robin Jugas, Lenka Radova, Julia Bohosova, Tana Machackova, Leos Kren, Ondrej Slaby, Petr Jabandziev   +11 more
wiley   +1 more source

Geospatial Discrepancy of Chronic Hepatitis B and Hepatitis D Testing in Alberta: A Population-Based Spatial Analysis. [PDF]

J Viral Hepat
Tkachuk B, Couloigner I, Coffin CS, Jiang J, Bertazzon S, Shaheen AA.   +5 more
europepmc   +1 more source

Outcomes of adalimumab biosimilar nonmedical switches in children and young adults with inflammatory bowel disease

JPGN Reports, EarlyView.
Abstract Objectives Adalimumab biosimilars are as safe and effective compared to the originator. Adult patients with inflammatory bowel disease (IBD) who switched to a biosimilar have comparable outcomes, but pediatric data are limited. This study evaluates clinical outcomes of children and young adults with IBD following a nonmedical, insurance‐driven
Daniel Himelstein, Megan McNicol, Mahmoud Abdel‐Rasoul, Brendan M. Boyle, Hilary K. Michel, Ross Maltz   +5 more
wiley   +1 more source

Novel Ensemble Prediction Framework for Fast and Accurate Phase Prediction in FeNiCoCrAlCu High‐Entropy Alloys by Integrating Data Augmentation and Interpretable Methods

Materials Genome Engineering Advances, EarlyView.
A physics‐informed machine learning framework is established for phase prediction in FeNiCoCrAlCu HEA. Limited experimental data are expanded through GMM‐based augmentation, followed by descriptor calculation, Pearson‐PCA feature optimization, stacking ensemble classification, and SHAP interpretation, enabling accurate phase identification and ...
Ruixiao Zhang, Biao Chen, Ruihao Yuan, Yi Williams Wang, Jun Wang, Jinshan Li   +5 more
wiley   +1 more source