Results 61 to 70 of about 5,280 (195)

Acalabrutinib in Chronic Lymphocytic Leukemia: Pharmacology and Emerging Clinical Perspectives

European Journal of Haematology, EarlyView.
ABSTRACT Acalabrutinib, a second‐generation Bruton's tyrosine kinase inhibitor (BTKi), is characterized by enhanced specificity and selectivity for BTK with minimal off‐target effects, offering a significant evolution in the treatment of chronic lymphocytic leukemia (CLL). Its mechanism of action, a covalent binding to Cys481 within the BTK active site,
Gianluca Gaidano, Romano Danesi
wiley   +1 more source

Frontal‐Driven Water‐Mass Transformation in a Western Boundary Current: Evidence From the Yucatan Current

Geophysical Research Letters, Volume 53, Issue 5, 16 March 2026.
Abstract We report the recurrent formation of waters with thermohaline properties similar to Gulf Common Water (GCW) in the western Yucatan Channel, absent upstream in the Caribbean. Mooring observations and a partial submesoscale‐resolving model show that these Yucatan GCW forms locally when the Yucatan Current separates from the slope, intensifying a
Giovanni Durante, Julio Sheinbaum, Alejandro Domínguez‐Guadarrama, Julien Jouanno, Luna Hiron, Uwe Send, Homar Verdugo‐Ortega, Angel Ruiz‐Angulo   +7 more
wiley   +1 more source

Ocean Bottom Seismometers Provide Direct Measurements of Pulsed‐Structure and Turbulence of Turbidity Currents Overspilling From a Submarine Channel

Geophysical Research Letters, Volume 53, Issue 5, 16 March 2026.
Abstract Turbidity currents transport vast amounts of sediment, carbon, and heat along submarine channels, yet their overspill onto channel‐levees and abyssal mixing remain poorly constrained due to lack of direct observations. Ocean‐bottom seismometers (OBS) deployed on the Congo Canyon–Channel levees captured the structure and turbulence of overspill
Pascal Kunath, Hans van Haren, Peter J. Talling   +2 more
wiley   +1 more source

Daratumumab Treatment for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP): A Case Report

Annals of Clinical and Translational Neurology, Volume 13, Issue 3, Page 622-626, March 2026.
ABSTRACT Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune‐mediated neuropathy featuring progressive weakness, sensory deficits, and areflexia. While corticosteroids, intravenous immunoglobulin, and plasmapheresis are effective first‐line immunotherapies, a subset of patients remains treatment‐refractory.
Xueyu Zhang, Jianli Zhao, Xue Zhao, Xiaowei Hu, Zichun Xiao, Jie Wu, Xiaowen Li, Jing Xu, Yu‐Jing Li   +8 more
wiley   +1 more source

Real-Time and Long-Term Monitoring of Coastal Water Turbidity Using an Ocean Buoy Equipped with an ADCP

Sensors
In this study, an acoustic Doppler current profiler (ADCP) operating at 600 kHz was installed on an ocean data buoy in the Qigu waters, Taiwan, to gather real-time sound echo intensity data.
Jia-Wei Bian, Ching-Jer Huang
doaj   +1 more source

Morphological instability in restored intertidal flats: How anthropogenic structures drive early‐stage evolution

Earth Surface Processes and Landforms, Volume 51, Issue 3, March 2026.
The study focusses on the morphological evolution of worldwide restored intertidal flats. These intertidal flats initially experience high sedimentation rates after the opening of the connection with open waters. The anthropogenic structures cause high morphological instability and are eroded, leading to a self‐cannibalisation of the system.
Riccardo Brunetta, Samantha Crowell, Megan Elliott, Danika van Proosdij, Paolo Ciavola   +4 more
wiley   +1 more source

Ocean currents and acoustic backscatter data from shipboard ADCP measurements at three North Atlantic seamounts between 2004 and 2015

Data in Brief, 2018
Seamounts are amongst the most common physiographic structures of the deep-ocean landscape, but remoteness and geographic complexity have limited the systematic collection of integrated and multidisciplinary data in the past.
Christian Mohn, Anneke Denda, Svenja Christiansen, Manfred Kaufmann, Florian Peine, Barbara Springer, Robert Turnewitsch, Bernd Christiansen   +7 more
doaj   +1 more source

Interaction of internal waves with the seafloor on the Namibian shelf (SE Atlantic Ocean): Implications for seafloor geomorphology

Earth Surface Processes and Landforms, Volume 51, Issue 3, March 2026.
Over geological timescales, internal waves play a significant role in shaping the seafloor morphology. They generate nepheloid layers, slope‐parallel channels and escarpments with erosional surfaces. Abstract The long‐term impact of internal waves on sedimentation and seafloor geomorphology remains poorly constrained.
Elda Miramontes, Claudia Wienberg, Tilmann Schwenk, Christian Mohn, Nadezhda Lagunova, Ling Wang, Paul Wintersteller, Jürgen Titschack, Victor Oki, Ulrike Hanz, Furu Mienis, Sabrina Köper, Maren Walter, Dierk Hebbeln   +13 more
wiley   +1 more source

Field measurements and model predictions of turbulent kinetic energy in canopies of sparse vegetation under tidal flows

Limnology and Oceanography Letters, Volume 11, Issue 2, March 2026.
Abstract The presence of vegetation in aquatic environments alters hydrodynamics and sediment resuspension. A recent paradigm has suggested that turbulent kinetic energy (TKE) serves as a better predictor of sediment transport in aquatic canopies than bed shear stress.
Vinay Nelli, Julia C. Mullarney, Rémi Chassagne, William Nardin, Rafael O. Tinoco   +4 more
wiley   +1 more source

Deep characteristic learning model for real-time flow monitoring based on H-ADCP

Journal of Hydrology: Regional Studies
Study region: The Luohu hydrological station, located in southeastern China, which has unstable water level- discharge relationship caused by tides. Study focus: Real-time flow monitoring based on horizontal-acoustic Doppler current profiler (H-ADCP ...
Yu Li, Xin Zhao, Yibo Wang, Ling Zeng
doaj   +1 more source