Early Mechanisms of Retinal Degeneration in the harlequin Mouse [PDF]
, 2014 Retinal diseases are personally debilitating and expensive, yet many early disease mechanisms leading to their onset and progression remain poorly understood.
Dolinar, Eric
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High intensity exercise as a dishabituating stimulus restores counterregulatory responses in recurrently hypoglycemic rodents [PDF]
, 2017 Hypoglycemia is a major adverse effect of insulin therapy for people with type 1 diabetes (T1D). Profound defects in the normal counterregulatory response to hypoglycemia explain the frequency of hypoglycemia occurrence in T1D.
Ashford, Michael L. J. +4 more
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Inter-Tumor Heterogeneity-Melanomas Respond Differently to GM-CSF-Mediated Activation. [PDF]
, 2020 Granulocyte-monocyte colony stimulating factor (GM-CSF) is used as an adjuvant in various clinical and preclinical studies with contradictory results.
Ben-Menachem, Shlomit +8 more
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An observational cohort feasibility study to identify microvesicle and miRNA biomarkers of acute kidney injury following paediatric cardiac surgery [PDF]
, 2018 The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Objectives: Micro-RNA, small noncoding RNA fragments involved in gene regulation, and microvesicles ...
JnTala, Maria +9 more
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Acta Pharmaceutica Sinica BObesity is a significant risk factor for cancer and is associated with breast cancer metastasis. Nevertheless, the mechanism by which alterations in systemic metabolism affect tumor microenvironment (TME) and consequently influence tumor metastasis ...
Chao Chen +13 more
doaj
Mitochondrial biogenesis as a mechanism of adaptation of specific cell types of the reproductive axis [PDF]
, 2022 Sažetak: U potrazi za ulogom markera mitohondrijalne dinamike u adaptaciji ćelija reproduktivne osovine, sa posebnim fokusom na spermatozoide, dizajnirani su razliĉiti in vivo pristupi koji mimikriraju situacije vezane za poremećenu homeostazu ...
Starovlah, Isidora
core
The Emerging Role of Soluble Adenylyl Cyclase in Primary Biliary Cholangitis
Digestive Diseases, 2017 Background: Primary biliary cholangitis (PBC; previously referred to as primary biliary cirrhosis) is a chronic fibrosing cholangiopathy with the signature of an autoimmune disease and features of intrahepatic cholestasis.
Jung-Chin Chang +2 more
semanticscholar +1 more source
Central role of soluble adenylyl cyclase and cAMP in sperm physiology [PDF]
, 2014 Cyclic adenosine 3′,5′-monophosphate (cAMP), the first second messenger to be described, plays a central role in cell signaling in a wide variety of cell types.
Buffone, Mariano Gabriel +3 more
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Thiol changes during epididymal maturation: a link to flagellar angulation in mouse spermatozoa?
Andrology, 2013 Caput epididymal wild‐type spermatozoa and cauda epididymal spermatozoa from mice null for the adenylyl cyclase Adcy10 gene are immotile unless stimulated by a membrane‐permeant cyclic AMP analogue.
T. Ijiri +6 more
semanticscholar +1 more source
Type 2 diabetes genetic association database manually curated for the study design and odds ratio [PDF]
, 2010 Background The prevalence of type 2 diabetes has reached epidemic proportions worldwide, and the incidence of life-threatening complications of diabetes through continued exposure of tissues to high glucose levels is increasing.
AD Johnson +16 more
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