Genetic etiology of Asthenozoospermia: A review
Fiyz̤, 2019 Background: Asthenozoospermia, as the most prevalent cause of male infertility, is defined as low percentage of progressively motile spermatozoa per ejaculate.
Arvand Akbari +3 more
doaj
Intracellular Ca2+ threshold reversibly switches flagellar beat off and on†
Biology of Reproduction, 2018 Sperm motility is essential for fertilization. The asymmetry of flagellar beat in spermatozoa is finely regulated by intracellular calcium concentration ([Ca2+]i).
C. Sánchez-Cárdenas +6 more
semanticscholar +1 more source
Non-canonical regulation of glycogenolysis and the Warburg phenotype by soluble adenylyl cyclase
bioRxiv, 2020 Cyclic AMP is produced in cells by two very different types of adenylyl cyclases: the canonical transmembrane adenylyl cyclases (tmACs, ADCY1∼9) and the evolutionarily more conserved soluble adenylyl cyclase (sAC, ADCY10).
Jung-Chin Chang +8 more
semanticscholar +1 more source
Exome Sequencing and Rare Variant Analysis Reveals Multiple Filaggrin Mutations in Bangladeshi Families with Atopic Eczema and Additional Risk Genes [PDF]
, 2018 M.P was supported by a Fellowship from the German Research Foundation (DFG). This work received infrastructure support through the DFG Cluster of Excellence “Inflammation at Interfaces” (grants EXC306 and EXC306/2), and was supported by grants (WE2678/
Alan D. Irvine +34 more
core +4 more sources
Global metabolic responses of the lenok (Brachymystax lenok) to thermal stress [PDF]
, 2019 High temperature is a powerful stressor for fish living in natural and artificial environments, especially for cold water species. Understanding the impact of thermal stress on physiological processes of fish is crucial for better cultivation and ...
Bureau, Dominique P. +8 more
core +1 more source
Early Mechanisms of Retinal Degeneration in the harlequin Mouse [PDF]
, 2014 Retinal diseases are personally debilitating and expensive, yet many early disease mechanisms leading to their onset and progression remain poorly understood.
Dolinar, Eric
core +1 more source
The Emerging Role of Soluble Adenylyl Cyclase in Primary Biliary Cholangitis
Digestive Diseases, 2017 Background: Primary biliary cholangitis (PBC; previously referred to as primary biliary cirrhosis) is a chronic fibrosing cholangiopathy with the signature of an autoimmune disease and features of intrahepatic cholestasis.
Jung-Chin Chang +2 more
semanticscholar +1 more source
Inter-Tumor Heterogeneity-Melanomas Respond Differently to GM-CSF-Mediated Activation. [PDF]
, 2020 Granulocyte-monocyte colony stimulating factor (GM-CSF) is used as an adjuvant in various clinical and preclinical studies with contradictory results.
Ben-Menachem, Shlomit +8 more
core +1 more source
Thiol changes during epididymal maturation: a link to flagellar angulation in mouse spermatozoa?
Andrology, 2013 Caput epididymal wild‐type spermatozoa and cauda epididymal spermatozoa from mice null for the adenylyl cyclase Adcy10 gene are immotile unless stimulated by a membrane‐permeant cyclic AMP analogue.
T. Ijiri +6 more
semanticscholar +1 more source