Results 141 to 150 of about 1,033 (153)

Jinwu Jiangu Capsule Alleviates Rheumatoid Arthritis Symptoms by Regulating the ADCY10 and cAMP/RANKL Pathways

open access: closedJournal of Ethnopharmacology
Rheumatoid arthritis (RA) is a systemic autoimmune disease that primarily affects joints and damages other tissues, including the heart, kidneys, lungs, digestive system, eyes, skin and nervous system. Jinwu Jiangu Capsule (JWJG) is effective in tonifying kidneys, activating blood circulation, and dispelling wind and dampness.
Qiuyi Wang   +9 more
semanticscholar   +4 more sources

Two novel heterozygous ADCY10 variants identified in Chinese pediatric patients with absorptive hypercalciuria: case report and literature review

open access: closedJournal of Genetics
Absorptive hypercalciuria (AH) is a prevalent cause of kidney stones, and the adenylate cyclase 10 (ADCY10) gene is a rare causative gene of AH. This study aims to investigate the genotypic and phenotypic characteristics of patients with AH caused by ADCY10 gene mutations.
Yucheng Ge   +5 more
semanticscholar   +4 more sources
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Adenylyl cyclase 10 is differentially expressed in the lymph nodes of patients with metastatic breast cancer.

, 2021
Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). Between the breast and the brain reside the secondary lymphoid organ, the lymph nodes.
Shahan Mamoor
semanticscholar   +1 more source

Bovine serum albumin‐induced calcium influx triggers soluble adenylyl cyclase activation and cyclic AMP signalling pathways in mouse sperm capacitation

Journal of Physiology
Sperm capacitation involves a series of biochemical and physiological changes essential for fertilization. A critical regulator of capacitation, the soluble adenylyl cyclase (sAC; ADCY10)‐dependent production of the second messenger cyclic AMP (cAMP ...
G. Luque   +13 more
semanticscholar   +1 more source

Soluble adenylyl cyclase (sAC) regulates calcium signaling in the vascular endothelium

The FASEB Journal, 2019
The vascular endothelium acts as a selective barrier between the bloodstream and extravascular tissues. Intracellular [Ca2+]i signaling is essential for vasoactive agonist‐induced stimulation of endothelial cells (ECs), typically including Ca2+ release ...
Mirja Mewes   +9 more
semanticscholar   +1 more source

Repeated immobilization stress disturbed steroidogenic machinery and stimulated the expression of cAMP signaling elements and adrenergic receptors in Leydig cells.

American Journal of Physiology. Endocrinology and Metabolism, 2012
This study was designed to evaluate the effect of acute (2 h daily) and repeated (2 h daily for 2 or 10 consecutive days) immobilization stress (IMO) on: 1) the steroidogenic machinery homeostasis; 2) cAMP signaling; and the expression of receptors for ...
N. Stojkov   +5 more
semanticscholar   +1 more source

Use of whole-exome sequencing to identify a novel ADCY10 mutation in a patient with nephrolithiasis.

open access: closed, 2020
Chen-Yu Wang   +6 more
openalex  

Integrative multi-target analysis of Urtica dioica for gout arthritis treatment: a network pharmacology and clustering approach.

In Silico Pharmacology
Maryam Qasmi   +4 more
semanticscholar   +1 more source

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