Results 131 to 140 of about 2,548 (156)
Cloning, Chromosomal Mapping, and Regulatory Properties of the Human Type 9 Adenylyl Cyclase (ADCY9)
Genomics, 1998 The type 9 adenylyl cyclase (AC9) is a widely distributed adenylyl cyclase that was originally cloned from a mouse cDNA library. Here we report the cloning, chromosomal mapping, and regulatory properties of human AC9 (HGMW-approved symbol ADCY9). Although the human AC9 sequence shows 86% homology with mouse AC9, divergence at the C2a/C2b junction ...
Beth M. Hacker +7 more
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Adcy9 Gene Inactivation Improves Cardiac Function After Myocardial Infarction in Mice
Canadian Journal of Cardiology, 2023 Polymorphisms in the adenylate cyclase 9 (ADCY9) gene influence the benefits of the cholesteryl ester transfer protein (CETP) modulator dalcetrapib on cardiovascular events after acute coronary syndrome. We hypothesized that Adcy9 inactivation could improve cardiac function and remodelling following myocardial infarction (MI) in absence of CETP ...
Marine Ferron +11 more
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Gene, 2023 Asthma is a respiratory disease caused by the interaction of genetic and environmental factors. The adenylyl cyclase type 9 (ADCY9) enzyme produces the cyclic-adenosinemonophosphate (cAMP), important mediator involved in bronchodilation and immunomodulatory response.
Helena Mariana Pitangueira Teixeira +10 more
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Assessment of ADCY9 polymorphisms and colorectal cancer risk in the Chinese Han population
The Journal of Gene Medicine, 2020 AbstractBackgroundRecently, ADCY9 has been found to be highly expressed in colon cancer, and high ADCY9 expressionis a poor prognostic factor of colon cancer. However, no study has reported on the relationship between single nucleotide polymorphisms (SNPs) of ADCY9 and colorectal cancer risk in the Chinese Han population.MethodsTo evaluate the ...
Haiyue Li +8 more
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Upregulated microRNA-210-3p improves sevoflurane-induced protective effect on ventricular remodeling in rats with myocardial infarction by inhibiting ADCY9 [PDF]
Functional & Integrative Genomics, 2022 Abstract ObjectiveMyocardial infarction (MI) is a significant cause of death and disability, and sevoflurane (sevo) can protect myocardium in clinic. We aim to assess the effects of miR-210-3p on MI rats undergoing sevo treatment with the involvement of adenylyl cyclase type 9 (ADCY9).MethodsRat MI models were constructed by ligation of the ...
Yahui Wu +3 more
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