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Asthma is a respiratory disease caused by the interaction of genetic and environmental factors. The adenylyl cyclase type 9 (ADCY9) enzyme produces the cyclic-adenosinemonophosphate (cAMP), important mediator involved in bronchodilation and immunomodulatory response.
H. Teixeira +10 more
semanticscholar +4 more sources
Assessment of ADCY9 polymorphisms and colorectal cancer risk in the Chinese Han population
Recently, ADCY9 has been found to be highly expressed in colon cancer, and high ADCY9 expressionis a poor prognostic factor of colon cancer. However, no study has reported on the relationship between single nucleotide polymorphisms (SNPs) of ADCY9 and ...
Haiyue Li +8 more
semanticscholar +4 more sources
AbstractChromosome 16p13 has been shown to display modest linkage signals for mood disorders in a number of studies. An interesting candidate gene in this region is the adenylate cyclase (AC) type 9 gene (ADCY9). ACs are critical in neuronal signaling, and perturbation of brain AC activity has been reported in mood disorder postmortem brains.
T. Toyota +7 more
semanticscholar +4 more sources
Towards Precision Secondary Prevention: Pharmacogenetic Insights from the Dalcetrapib-ADCY9 Pathway.
Amal Aidoud +2 more
semanticscholar +3 more sources
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Journal of Cardiovascular Pharmacology, 2021
: Atherosclerosis has been effectively avoided with many therapies that lower low-density lipoprotein cholesterol. However, significant cardiovascular burden remains.
D. Black +3 more
semanticscholar +3 more sources
: Atherosclerosis has been effectively avoided with many therapies that lower low-density lipoprotein cholesterol. However, significant cardiovascular burden remains.
D. Black +3 more
semanticscholar +3 more sources

