Results 61 to 70 of about 1,135 (126)
Higher expression of mir‐31‐5p is associated with reduced risk of head and neck keloid recurrence following surgical resection
Laryngoscope Investigative Otolaryngology, Volume 9, Issue 6, December 2024.MicroRNA‐31‐5p expression in head and neck keloid formalin fixed paraffin embedded tissue is associated with recurrence, 1 year following treatment with surgery. MicroRNA‐3‐5p potential as a prognostic biomarker should be further investigated. Abstract Objective
In this study, we aimed to evaluate mir‐31‐5p as a prognostic biomarker of keloid disease ...Albert M. Levin, Oghenefejiro Okifo, Katherine Buhl, Takahiro Ouchi, Bianca Parker, Jessica Tan, Indrani Datta, Xiangguo Dai, Yalei Chen, Nallasivam Palanisamy, Jesse Veenstra, Shannon Carskadon, Jia Li, David Ozog, Christian E. Keller, Dhananjay Chitale, Kevin R. Bobbitt, Howard C. Crawford, Nina Steele, Qing‐Sheng Mi, Lamont R. Jones +20 morewiley +1 more sourceModulation of the neurotransmitter systems through the anti-inflammatory and antidepressant-like effects of squalene from Aurantiochytrium sp. [PDF]
, 2019 Although algae have been the focal point of biofuel research, studies on their biological activities have been limited. In recent years, however, the importance of algae as sources of functional ingredients has been recognized due to their health ...Farhana Ferdousi, Hiroko ISODA, Kazunori SASAKI, Kenichi Tominaga, Mahmoud Ben Othman, Makoto WATANABE, Masaki Yoshida, 佐々木 一憲, 渡邉 信, 礒田 博子 +9 morecore +2 more sourcesThe epigenetic mechanisms of adaption to the hot and humid climate in Hu sheep (Ovis aries)
Physiological Reports, Volume 12, Issue 24, December 2024.Abstract
Hu sheep is characterized by its excellent fecundity and high adaptability to various ecological environments. To reveal the molecular basis involved in Hu sheep, we first examined the 10 index of neuroendocrine and metabolism in blood in Hu sheep during non‐stress period (April–May) and stress period (July–August) using ELISA, including CRH ...Hangxing Ren, Jing Jiang, Jie Li, Xiaoyan Sun, Cancan Chen, Liangjia Liu, Shipeng Lv, Minghao Qu, Yuxue Fan, Peng Zhou, Gaofu Wang +10 morewiley +1 more sourceAssociations between Gene-Gene Interaction and Overweight/Obesity of 12-Month-Old Chinese Infants
BioMed Research International, 2022 Background Childhood overweight and obesity (OW/OB) is a worldwide public health problem, and its genetic risks remain unclear. Objectives To investigate risks of OW/OB associated with genetic variances in SEC16B rs543874 and rs10913469, BDNF rs11030104 ...Hong Mei, Bao Yin, Wenhong Yang, Jingli Zhang, Hongyan Lu, Xiaobin Qi, Wenhua Mei, Hongzhong Zhang, Jianduan Zhang +8 moresemanticscholar +1 more sourceEpstein-Barr Virus EBER Transcripts Affect miRNA-Mediated Regulation of Specific Targets and Are Processed to Small RNA Species [PDF]
, 2018 The oncogenic Epstein-Barr virus (EBV) expresses 44 mature microRNAs and two non-coding EBER RNAs of 167 (EBER1) and 172 (EBER2) nt length. MiRNA profiling of NK/T cell lines and primary cells and Northern blotting of EBV-infected cell lines and primary ...Alles, Julia, Eichner, Norbert, Grässer, Friedrich A., Hamilton, Andrew, Hasler, Daniele, Kazmi, Syed Mohammad Ali, Marx, Stefanie, Meister, Gunter, Reinhardt, Richard, Schlegel, Linda, Tesson, Mathias, Wilson, Joanna B. +11 morecore +1 more sourceParaoxonase‐2 agonist vutiglabridin promotes autophagy activation and mitochondrial function to alleviate non‐alcoholic steatohepatitis
British Journal of Pharmacology, Volume 181, Issue 19, Page 3717-3742, October 2024.Abstract Background and Purpose
Only limited therapeutic agents have been developed for non‐alcoholic steatohepatitis (NASH). Glabridin, a promising anti‐obesity candidate, has only limited druggability due to its low in vivo chemical stability and bioavailability.Gu‐Choul Shin, Hyeong Min Lee, Nayeon Kim, Jihyeon Hur, Sang‐Ku Yoo, Yun Sun Park, Hyung Soon Park, Dongryeol Ryu, Min‐Ho Park, Jung Hee Park, Sang‐Uk Seo, Leo Sungwong Choi, Martin Rønn Madsen, Michael Feigh, Kwang Pyo Kim, Kyun‐Hwan Kim +15 morewiley +1 more sourceIntegration of multiomics data identifies candidate genes influencing pH levels in Beijing Black pigs
Animal Research and One Health, Volume 2, Issue 3, Page 260-272, August 2024.To explore the genetic mechanism of pH values, we measured the pH values at 2 h (pH2h) and 24 h (pH24h) postmortem in the longissimus dorsi muscle of Beijing Black pigs. A total of 614 Beijing Black pigs were genotyped by the Illumina Porcine 50K SNP Chip. We conducted a genome‐wide association study and RNA sequencing (RNA‐seq) analysis.Jingjing Tian, Naiqi Niu, Xiaoqing Wang, Liangyu Shi, Liyu Yang, Mianyan Li, Lijun Shi, Xin Liu, Hongmei Gao, Xinhua Hou, Ligang Wang, Lixian Wang, Longchao Zhang, Fuping Zhao +13 morewiley +1 more sourceGenome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Nature Genetics, 2013 Approaches exploiting trait distribution extremes may be used to identify loci associated with common traits, but it is unknown whether these loci are generalizable to the broader population.S. I. Berndt, S. Gustafsson, R. Mägi, A. Ganna, E. Wheeler, M. Feitosa, A. Justice, K. Monda, Damien C. Croteau-Chonka, F. Day, T. Esko, T. Fall, T. Ferreira, Davide Gentilini, A. Jackson, J. Luan, J. Randall, S. Vedantam, C. Willer, T. Winkler, A. Wood, T. Workalemahu, Yi-Juan Hu, S. Lee, Liming Liang, Dan-yu Lin, J. Min, B. Neale, G. Thorleifsson, Jian Yang, E. Albrecht, N. Amin, J. Bragg-Gresham, G. Cadby, M. den Heijer, N. Eklund, K. Fischer, A. Goel, J. Hottenga, J. Huffman, I. Jarick, Å. Johansson, T. Johnson, S. Kanoni, M. Kleber, I. König, K. Kristiansson, Z. Kutalik, C. Lamina, C. Lecoeur, Guo Li, M. Mangino, W. McArdle, C. Medina-Gomez, Martina Müller-Nurasyid, Julius S. Ngwa, I. Nolte, L. Paternoster, S. Pechlivanis, M. Perola, M. Peters, Michael H. Preuss, L. Rose, Jianxin Shi, D. Shungin, A. Smith, R. Strawbridge, I. Surakka, A. Teumer, M. Trip, J. Tyrer, Jana V. van Vliet-Ostaptchouk, L. Vandenput, L. Waite, Jinghua Zhao, D. Absher, F. Asselbergs, M. Atalay, A. Attwood, A. Balmforth, H. Basart, J. Beilby, L. Bonnycastle, Paolo Brambilla, M. Bruinenberg, Harry Campbell, D. Chasman, P. Chines, F. Collins, J. Connell, W. Cookson, U. de Faire, F. de Vegt, Mariano Dei, M. Dimitriou, S. Edkins, K. Estrada, David M. Evans, M. Farrall, M. M. Ferrario, J. Ferrières, L. Franke, F. Frau, P. Gejman, H. Grallert, Henrik Grönberg, V. Gudnason, Alistair S. Hall, Per Hall, Anna-Liisa Hartikainen, C. Hayward, N. Heard-Costa, Andrew C. Heath, J. Hebebrand, G. Homuth, Frank Hu, S. Hunt, Elina Hyppönen, C. Iribarren, K. Jacobs, J. Jansson, A. Jula, M. Kähönen, S. Kathiresan, F. Kee, K. Khaw, M. Kivimäki, Wolfgang Koenig, A. Kraja, M. Kumari, K. Kuulasmaa, J. Kuusisto, J. Laitinen, T. Lakka, C. Langenberg, L. Launer, L. Lind, J. Lindström, Jianjun Liu, Antonio Liuzzi, M. Lokki, M. Lorentzon, P. Madden, P. Magnusson, P. Manunta, Diana Marek, Winfried März, I. M. Leach, Barbara McKnight, S. Medland, E. Mihailov, L. Milani, G. Montgomery, V. Mooser, Thomas W. Mühleisen, P. Munroe, A. Musk, Narisu Narisu, G. Navis, G. Nicholson, E. Nohr, Ken K. Ong, B. Oostra, Colin N. A. Palmer, A. Palotie, J. Peden, Nancy L Pedersen, Annette Peters, O. Polašek, A. Pouta, P. Pramstaller, I. Prokopenko, C. Pütter, A. Radhakrishnan, O. Raitakari, A. Rendon, F. Rivadeneira, I. Rudan, T. Saaristo, J. Sambrook, A. Sanders, S. Sanna, J. Saramies, S. Schipf, S. Schreiber, Heribert Schunkert, So-Youn Shin, S. Signorini, J. Sinisalo, Boris Skrobek, N. Soranzo, A. Stančáková, K. Stark, J. Stephens, K. Stirrups, R. Stolk, M. Stumvoll, A. Swift, E. Theodoraki, B. Thorand, D. Tregouet, E. Tremoli, M. M. van der Klauw, J. V. van Meurs, S. Vermeulen, J. Viikari, J. Virtamo, V. Vitart, G. Waeber, Z. Wang, E. Widén, Sarah H Wild, G. Willemsen, B. Winkelmann, J. Witteman, B. Wolffenbuttel, A. Wong, Alan F. Wright, M. Zillikens, P. Amouyel, Bernhard O. Boehm, E. Boerwinkle, D. Boomsma, M. Caulfield, S. Chanock, L. Cupples, D. Cusi, G. Dedoussis, J. Erdmann, J. Eriksson, P. Franks, P. Froguel, C. Gieger, U. Gyllensten, A. Hamsten, T. Harris, C. Hengstenberg, A. Hicks, A. Hingorani, A. Hinney, A. Hofman, K. Hovingh, K. Hveem, T. Illig, M. Jarvelin, K. Jöckel, S. Keinanen-Kiukaanniemi, L. Kiemeney, D. Kuh, M. Laakso, T. Lehtimäki, D. Levinson, N. G. Martin, A. Metspalu, Andrew D. Morris, Markku S Nieminen, I. Njølstad, Claes Ohlsson, A. Oldehinkel, W. Ouwehand, L. Palmer, B. Penninx, C. Power, M. Province, B. Psaty, Lu Qi, R. Rauramaa, P. Ridker, S. Ripatti, V. Salomaa, N. Samani, H. Snieder, T. I. Sørensen, T. Spector, K. Stefansson, A. Tönjes, J. Tuomilehto, A. Uitterlinden, M. Uusitupa, P. van der Harst, P. Vollenweider, H. Wallaschofski, N. Wareham, Hugh Watkins, H. Wichmann, James F. Wilson, G. Abecasis, T. Assimes, I. Barroso, M. Boehnke, I. Borecki, P. Deloukas, C. Fox, T. Frayling, L. Groop, Talin Haritunian, I. Heid, David J. Hunter, R. C. Kaplan, F. Karpe, M. Moffatt, K. Mohlke, J. O’Connell, Y. Pawitan, E. Schadt, D. Schlessinger, V. Steinthorsdottir, David P. Strachan, U. Thorsteinsdóttir, C. V. van Duijn, P. Visscher, A. Di Blasio, J. Hirschhorn, C. Lindgren, Andrew P Morris, D. Meyre, A. Scherag, M. McCarthy, Elizabeth K. Speliotes, K. North, Ruth J. F. Loos, E. Ingelsson +321 moresemanticscholar +1 more sourceGene expression within the extended amygdala of 5 pairs of rat lines selectively bred for high or low ethanol consumption [PDF]
, 2013 The objectives of this study were to determine innate differences in gene expression in 2 regions of the extended amygdala between 5 different pairs of lines of male rats selectively bred for high or low ethanol consumption: a) alcohol-preferring (P) vs. Bell, Richard L., Colombo, Giancarlo, Ding, Zheng-Ming, Edenberg, Howard J., Hyytia, Petri, Kimpel, Mark W., Liang, Tiebing, Lumeng, Lawrence, McBride, William J., McClintick, Jeanette N. +9 morecore +1 more source