Results 61 to 70 of about 1,135 (126)

Higher expression of mir‐31‐5p is associated with reduced risk of head and neck keloid recurrence following surgical resection

open access: yesLaryngoscope Investigative Otolaryngology, Volume 9, Issue 6, December 2024.
MicroRNA‐31‐5p expression in head and neck keloid formalin fixed paraffin embedded tissue is associated with recurrence, 1 year following treatment with surgery. MicroRNA‐3‐5p potential as a prognostic biomarker should be further investigated. Abstract Objective In this study, we aimed to evaluate mir‐31‐5p as a prognostic biomarker of keloid disease ...
Albert M. Levin   +20 more
wiley   +1 more source

Drivers of genomic diversity and phenotypic development in early phases of domestication in Hermetia illucens

open access: yesInsect Molecular Biology, Volume 33, Issue 6, Page 756-776, December 2024.
Random drift rather than selection is the primary evolutionary force driving genomic and phenotypic variation in BSF populations during early phases of domestication. Functional trade‐offs between production and fitness traits were observed in BSF populations.
Kelvin L. Hull   +5 more
wiley   +1 more source

Modulation of the neurotransmitter systems through the anti-inflammatory and antidepressant-like effects of squalene from Aurantiochytrium sp. [PDF]

open access: yes, 2019
Although algae have been the focal point of biofuel research, studies on their biological activities have been limited. In recent years, however, the importance of algae as sources of functional ingredients has been recognized due to their health ...
Farhana Ferdousi   +9 more
core   +2 more sources

The epigenetic mechanisms of adaption to the hot and humid climate in Hu sheep (Ovis aries)

open access: yesPhysiological Reports, Volume 12, Issue 24, December 2024.
Abstract Hu sheep is characterized by its excellent fecundity and high adaptability to various ecological environments. To reveal the molecular basis involved in Hu sheep, we first examined the 10 index of neuroendocrine and metabolism in blood in Hu sheep during non‐stress period (April–May) and stress period (July–August) using ELISA, including CRH ...
Hangxing Ren   +10 more
wiley   +1 more source

Associations between Gene-Gene Interaction and Overweight/Obesity of 12-Month-Old Chinese Infants

open access: yesBioMed Research International, 2022
Background Childhood overweight and obesity (OW/OB) is a worldwide public health problem, and its genetic risks remain unclear. Objectives To investigate risks of OW/OB associated with genetic variances in SEC16B rs543874 and rs10913469, BDNF rs11030104 ...
Hong Mei   +8 more
semanticscholar   +1 more source

Epstein-Barr Virus EBER Transcripts Affect miRNA-Mediated Regulation of Specific Targets and Are Processed to Small RNA Species [PDF]

open access: yes, 2018
The oncogenic Epstein-Barr virus (EBV) expresses 44 mature microRNAs and two non-coding EBER RNAs of 167 (EBER1) and 172 (EBER2) nt length. MiRNA profiling of NK/T cell lines and primary cells and Northern blotting of EBV-infected cell lines and primary ...
Alles, Julia   +11 more
core   +1 more source

Paraoxonase‐2 agonist vutiglabridin promotes autophagy activation and mitochondrial function to alleviate non‐alcoholic steatohepatitis

open access: yesBritish Journal of Pharmacology, Volume 181, Issue 19, Page 3717-3742, October 2024.
Abstract Background and Purpose Only limited therapeutic agents have been developed for non‐alcoholic steatohepatitis (NASH). Glabridin, a promising anti‐obesity candidate, has only limited druggability due to its low in vivo chemical stability and bioavailability.
Gu‐Choul Shin   +15 more
wiley   +1 more source

Integration of multiomics data identifies candidate genes influencing pH levels in Beijing Black pigs

open access: yesAnimal Research and One Health, Volume 2, Issue 3, Page 260-272, August 2024.
To explore the genetic mechanism of pH values, we measured the pH values at 2 h (pH2h) and 24 h (pH24h) postmortem in the longissimus dorsi muscle of Beijing Black pigs. A total of 614 Beijing Black pigs were genotyped by the Illumina Porcine 50K SNP Chip. We conducted a genome‐wide association study and RNA sequencing (RNA‐seq) analysis.
Jingjing Tian   +13 more
wiley   +1 more source

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

open access: yesNature Genetics, 2013
Approaches exploiting trait distribution extremes may be used to identify loci associated with common traits, but it is unknown whether these loci are generalizable to the broader population.
S. I. Berndt   +321 more
semanticscholar   +1 more source

Gene expression within the extended amygdala of 5 pairs of rat lines selectively bred for high or low ethanol consumption [PDF]

open access: yes, 2013
The objectives of this study were to determine innate differences in gene expression in 2 regions of the extended amygdala between 5 different pairs of lines of male rats selectively bred for high or low ethanol consumption: a) alcohol-preferring (P) vs.
Bell, Richard L.   +9 more
core   +1 more source

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