Results 241 to 250 of about 4,479,240 (304)

Experimental Study on the Nonlinearity of Added Resistance

Journal of the Society of Naval Architects of Korea
Dong-Min Park, Young Jae Oh, Seunghyun Hwang, Yong-Ju Kwon   +3 more
openaire   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

The metal-uptake-deficient Escherichia coli strain GR536 contains the ϕ80 prophage. [PDF]

Access Microbiol
Shimpo A, Augustine J, Acton LJ, Hall LJ, Chivers P.   +4 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Correction to "Velocity Loss During Resistance Training: Implications for Concurrent Training Adaptations". [PDF]

Scand J Med Sci Sports
europepmc   +1 more source

Whole-genome sequencing guides the successful treatment of extensively drug-resistant TB. [PDF]

IJTLD Open
Makamure B, Phelan J, Bandason T, Chipinduro M, Mutsvangwa J, Metcalfe JZ, Fernandez FT, Manasa J.   +7 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

The Effect of Hydrated Lime on the Low-Temperature Properties of Foamed Asphalt Mixture (FAM). [PDF]

Materials (Basel)
Iwański MM, Cholewińska M, Podsiadło M.   +2 more
europepmc   +1 more source

Biohybrid nanovesicle-mediated targeted delivery of HSP90 inhibitor for enhanced sorafenib therapy of hepatocellular carcinoma after radiofrequency ablation. [PDF]

Mater Today Bio
Jiang A, Zhou X, Zhao J, Zou S, Ding J, Zhang J, Lei L, Jin Q, Tang Z.   +8 more
europepmc   +1 more source