Results 191 to 200 of about 926,997 (405)

Neurobiology of addiction: a neurocircuitry analysis.

open access: yesLancet psychiatry, 2016
G. Koob, N. Volkow
semanticscholar   +1 more source

Psychopathology of addictions

open access: yesRevista Psicopatologia Fenomenológica Contemporânea, 2014
This paper intends to examine, both from a psychopathological and a phenomenological perspective, the state of “being-at-the-world”, which is common in drug addicted people. Past abuse, as well as present abuse, are crucial in the modification of the psychiatric impact in the history of drug abuse.
openaire   +5 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

An integrated knowledge mobilization approach to substance use health

open access: yesHealth Research Policy and Systems
The Canadian Centre on Substance Use and Addiction (CCSA) has a mandate to provide national leadership in evidence-informed analysis and knowledge mobilization to advance solutions that reduce substance-related harms. Doing this work effectively requires
Sheena Taha   +5 more
doaj   +1 more source

Drug Addiction in the Industries [PDF]

open access: green, 1922
Blair, S. Thos
openalex   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

The association of psychological distress and economic and health worries with tobacco smoking behavior during the COVID-19 pandemic: a two-year longitudinal cohort study

open access: yesBMC Public Health
Background The COVID-19 pandemic and other life events may trigger worries and psychological distress. These impacts may lead to unhealthy behaviors, such as tobacco smoking, but the degree of such associations is unclear.
Silvia Eiken Alpers   +8 more
doaj   +1 more source

Internet addiction and loneliness among children and adolescents in the education setting: an empirical pilot study [PDF]

open access: yes, 2014
Research into various behavioural addictions has shown that such behaviour can negatively impact psychological wellbeing. One behavioural addiction that has been increasingly studied empirically is that of Internet Addiction (IA).
Griffiths, MD, Patrão, IM, Pontes, HM
core  

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