Results 211 to 220 of about 960,477 (390)
Addiction to car use and dynamic elasticity measures in France [PDF]
This article presents a microeconometric analysis of the annual mileage travelled by French households with their personal cars, defining their automobility. To feature car use dependence, the rational addiction model of Becker et al.
Laurent Hivert +2 more
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Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Addiction and Cue-Conditioned Cognitive Processes [PDF]
We propose an economic theory of addiction based on the premise that cognitive mechanisms such as attention affect behavior independently of preferences. We argue that the theory is consistent with foundational evidence (e.g.
Antonio Rangel, B. Douglas Bernheim
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Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications
Nature Reviews Neuroscience, 2011 Rita Z. Goldstein, N. Volkow
semanticscholar +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
OBESITY AND NUTRIENT CONSUMPTION: A RATIONAL ADDICTION? [PDF]
This study tests for a rational addiction to food nutrients as a potential explanation for the obesity epidemic. A random coefficients (mixed) logit model applied to household scanner data finds evidence of a strong, forward-looking addiction to ...
Patterson, Paul M. +2 more
core +1 more source