Results 221 to 230 of about 474,753 (298)

The case for developing pharmacist workforce capacity in addiction medicine [PDF]

, 2019
Suzanne Nielsen, Beth Sproule
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

The impact of table tennis intervention on short video addiction among college students in China: the chained mediation effect of cognitive bias and self-control. [PDF]

Front Psychol
Wang K, Sun J, Han J, Wu Z.
europepmc   +1 more source

Drug Addiction: Updating Actions to Habits to Compulsions Ten Years On.

Annual Review of Psychology, 2016
B. Everitt, T. Robbins
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Prevalence and determinants of food addiction among Palestinian university students: a cross-sectional study. [PDF]

Eat Weight Disord
Hamdan M, Al-Amouri F, Jaber MM, Marbu D, Abed MT, Halayqa A, Al-Zabadi B, Qawasmeh E, Shaheen R, Badrasawi M.   +9 more
europepmc   +1 more source

PREVALENCE OF INTERNET ADDICTION AND ITS DEMOGRAPHIC DETERMINANTS: A CROSS-SECTIONAL ANALYSIS IN MALAYSIA

Malai Haniti S. A. Hamid, Nor Shafrin Ahmad, Rahimi Che Aman   +2 more
openalex   +2 more sources

Physical exercise moderates the mediating effect of depression between physical and psychological abuse in childhood and social network addiction in college students [PDF]

Wenjie Jia, Xin Zhang, Yuanyuan Ma, Guoying Yan, Yiyi Chen, Yang Liu   +5 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Adicción a internet: desarrollo y validación de un instrumento en escolares adolescentes de Lima, Perú Internet addiction: development and validation of an instrument in adolescent scholars in Lima, Perú

, 2011
Nelly Lam-Figueroa, Hans Contreras‐Pulache, Elizabeth Mori-Quispe, Martín Nizama-Valladolid, César Gutiérrez, Williams Hinostroza-Camposano, Erasmo Torrejón Reyes, Richard Hinostroza-Camposano, Elizabeth Coaquira-Condori, Willy David Hinostroza-Camposano   +9 more
openalex   +1 more source