Results 261 to 270 of about 926,997 (405)
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Translation and psychometric properties of the tamil version of the smartphone addiction scale- short version (SAS-SV-T) among adolescents: measurement invariance across gender. [PDF]
C A, Sahayam D B.
europepmc +1 more source
Multiple-Drug Addiction in New York City in a Selected Population Group: A Statistical Review [PDF]
Hans Abeles+3 more
openalex +1 more source
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
Cravings, Control, and Cessation: A Scoping Review of Perceptions of Nicotine Addiction. [PDF]
Temourian AA, Halliday DM, Song AV.
europepmc +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Toward healthy behavior: fear of missing out, smartphone, social networking addiction, and life satisfaction among medical students at Tanta University, Egypt. [PDF]
Younis EA, Mohammad AMA, Elsebaey AFA.
europepmc +1 more source