Stigma from healthcare professionals and care-limiting behaviors in individuals with substance use disorders: a mixed-methods study. [PDF]
Luderer M +6 more
europepmc +1 more source
Do Maladaptive Schemas Put Young People at Risk for Addiction?
Christian P. Müller
openalex +2 more sources
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Methamphetamine use disorder, perceived impacts, and associated factors among adults receiving care at Sri Lanka's National Institute of Mental Health: An analytical cross-sectional study. [PDF]
Nishshanka NAAI +5 more
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Impact of adolescent internet addiction on academic procrastination: the serial mediating role of self-control and anxiety. [PDF]
Wu Z +7 more
europepmc +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Policies and public health initiatives to mitigate the mental health impact of internet use among children and adolescents. [PDF]
Tadpatrikar A, Sharma MK, Murthy P.
europepmc +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source

