Results 341 to 350 of about 926,997 (405)

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source

Peer pressure, anxiety, and smartphone addiction among Chinese college students: a mediation analysis. [PDF]

BMC Psychol
Hung MT, Hung LC, Zhou Q, Huang Z.
europepmc   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Substance use disorders: a call for a staging paradigm. [PDF]

Transl Psychiatry
Bachi K, Hurd YL, Salsitz EA.
europepmc   +1 more source

A single gene mutation predicts response to immune checkpoint blockade in ovarian clear cell carcinoma

Molecular Oncology, EarlyView.
Loss‐of‐function mutations in the scaffold subunit of protein phosphatase 2A (PP2A), PPP2R1A, sensitize ovarian clear cell carcinoma to immune checkpoint blockade (ICB) by enhancing the interferon gamma response and promoting antitumor immune cell infiltration.
Matheus Henrique Dias, René Bernards
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Examining the prevalence of neck and hand disorders and its relationship with smartphone addiction in medical students. [PDF]

BMC Musculoskelet Disord
Rafiyan M, Azadchehr MJ, Fazeli AM, Jalalati N.   +3 more
europepmc   +1 more source

Reconstructing Cross-Cultural Meanings of Addiction Among Women from Three Countries. [PDF]

Int J Environ Res Public Health
Placek CD, Adair L, Jain I, Gupta S, Phadke V, Singh M.   +5 more
europepmc   +1 more source

Are depression, quality of life and life satisfaction associated with internet addiction? A cross-sectional study among Turkish university students. [PDF]

BMC Psychiatry
Sayili U, Kara B, Aydin SN, Siddikoglu E, Albayrak B, Erginoz E.   +5 more
europepmc   +1 more source

Anxiety mediates the effect of social media addiction on negative attentional bias: the moderating role of impulsivity. [PDF]

Front Psychiatry
Qiu R, Li Y, Gong Y, Guo Z, Cheng S, Li M, Zhu X.   +6 more
europepmc   +1 more source