Results 51 to 60 of about 9,344,708 (303)

Heritability of Addison’s disease and prevalence of associated autoimmunity in a cohort of 112,100 Swedish twins

Endocrine, 2017
PurposeThe pathophysiology behind autoimmune Addison’s disease (AAD) is poorly understood, and the relative influence of genetic and environmental factors remains unclear. In this study, we examined the heritability of AAD and explored disease-associated
J. Skov, J. Höijer, P. Magnusson, J. Ludvigsson, O. Kämpe, S. Bensing   +5 more
semanticscholar   +1 more source

Effect of steroid replacement on thyroid function and thyroid autoimmunity in Addison′ s disease with primary hypothyroidism

Indian Journal of Endocrinology and Metabolism, 2016
Background: Steroid replacement without thyroxine supplementation normalizes thyroid function test (TFT) in some but not all Addison's disease patients with primary hypothyroidism.
Jaya Prakash Sahoo, Jayakumar Selviambigapathy, Sadishkumar Kamalanathan, K Nagarajan, Muthupillai Vivekanandan   +4 more
doaj   +1 more source

Primary adrenal insufficiency - Addison's disease

Journal of Education, Health and Sport, 2022
Introduction and purpose Addison's syndrome is defined as primary adrenal insufficiency, the symptoms of which result from hormonal deficiencies: glucocorticosteroids, mineralocorticosteroids and androgens.
Jakub Metelski, Aleksandra Metelska, Dominika Sereda, Hubert Nieścior, Monika Szwed   +4 more
doaj   +1 more source

Diagnosis of oral pigmentations and malignant transformations [PDF]

, 1951
BackgroundOral pigmentation is a common finding in the mouth. Pigmentation can be either normal or abnormal discoloration of oral mucous membrane.
Eisen, Kleinegger, Gaeta, Hemminki, Hemminki, Hemminki, McGrath, Kauzman, Dereure, Birek, Kim, Weathers, Buchner, Gupta, Zaraa, Esen, Halder, Hedin, Hedin, Axell, Araki, Perusse, Marks, McAllan, Savage, Westbury, Meyerson, Buchner, Hicks, Goode, Whitt, Barker, Gorsky   +32 more
core   +1 more source

Schimidt Syndrome: An Unusual Cause of Hypercalcaemia [PDF]

Journal of Clinical and Diagnostic Research, 2016
Autoimmune polyglandular syndrome type 2 also known as Schmidt syndrome. It is a rare disorder involving a combination of Addison’s disease with autoimmune thyroid disease with or without type 1 diabetes mellitus.
Nisha Jose, George Prashanth Kurian
doaj   +1 more source

Extended exome sequencing identifies BACH2 as a novel major risk locus for Addison's disease

Journal of Internal Medicine, 2016
Autoimmune disease is one of the leading causes of morbidity and mortality worldwide. In Addison's disease, the adrenal glands are targeted by destructive autoimmunity. Despite being the most common cause of primary adrenal failure, little is known about
D. Eriksson, M. Bianchi, Nils Landegren, J. Nordin, Frida Dalin, A. Mathioudaki, G. Eriksson, L. Hultin‐Rosenberg, J. Dahlqvist, H. Zetterqvist, Andreas Karlsson, Anna Hallgren, F. Farias, E. Murén, K. Ahlgren, A. Lobell, G. Andersson, Karolina Tandre, S. R. Dahlqvist, P. Söderkvist, L. Rönnblom, A. Hulting, J. Wahlberg, O. Ekwall, P. Dahlqvist, J. Meadows, S. Bensing, S. Bensing, Kerstin Lindblad-Toh, Kerstin Lindblad-Toh, Olle Kämpe, Olle Kämpe, G. Pielberg   +32 more
semanticscholar   +1 more source

Identification of Compound Heterozygous CYP11A1 Variants via Reanalysis of Clinical Sequencing Data

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT A molecular diagnosis is currently achievable in approximately 50% of patients assessed by clinical geneticists at tertiary care centres. Next‐Generation Sequencing Panels contain a defined group of genes associated with a clinically defined set of phenotypes.
Ana Acosta Bedón, Vahid Akbari, Ralph Rothstein, Alexandra Inman, Sanjiv Bhalla, Jianghong An, Jan M. Friedman, Rosanna Weksberg, Cornelius Boerkoel, Steven J. M. Jones, William T. Gibson   +10 more
wiley   +1 more source

Persistent dizziness and recurrent syncope due to HIV-associated Addison’s disease: Case report from a resource-limited setting

Southern African Journal of HIV Medicine, 2012
Addison’s disease or primary adrenal insufficiency is a well-recognised fatal endocrine condition among HIV-infected patients. HIV infection is associated with adrenal gland destruction and profound disruption of the hypothalamic-pituitary adrenal axis ...
D Kibirige, R Ssekitoleko, E Mutebi
doaj   +1 more source

Doença de addison de etiologia auto-imune [PDF]

, 1998
Autoimmune Addison's disease is a rare and potentially, fatal endocrinopathy, that can occur either isolated or as part of the types I and II polyglandular autoimmune syndromes (PAS).
Kater, Claudio Elias, Silva, Regina do Carmo   +1 more
core   +3 more sources

Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs

The Anatomical Record, EarlyView.
Abstract Crocodilians, together with birds, are the only extant relatives to many extinct archosaur groups, making them highly important for interpreting paleopathological conditions in a phylogenetic disease bracketing model. Despite this, comprehensive data on osteopathologies in crocodilians remain scarce.
Alexis Cornille, Kyla Beguesse, Ewan Wolff, Clemens Zinner, Patrick Asbach, François Clarac, Florian Witzmann   +6 more
wiley   +1 more source