Results 81 to 90 of about 9,344,708 (303)

Persistent isolated hypocortisolism following brief treatment with trilostane [PDF]

, 2008
A 12-year-old male neutered Miniature Poodle with confirmed pituitary-dependent hyperadrenocorticism was treated with trilostane. After three doses, it developed clinical and laboratory changes suggestive of isolated hypocortisolism ('atypical ...
Barker, Bell, Braddock, Chapman, Dunn, Eastwood, Feldman, Hoffman, Javadi, Kintzer, Lifton, Mantis, Neiger, Rao, Ruckstuhl, Russell, Sadek, Sieber-Ruckstuhl, Wenger, Witt   +19 more
core   +1 more source

Epidemiology and Genetics of Rheumatic Diseases Suggest a Constant Rate of DNA Damage as Underlying Cause

Immunology, EarlyView.
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley   +1 more source

Levothyroxine sodium oral solution to control thyroid function in a patient with hypothyroidism and celiac disease

Clinical Case Reports, 2021
Implementing a gluten‐free diet and switching to the levothyroxine oral solution significantly improved malabsorptive and hypothyroid symptoms in a patient with hypothyroidism, Addison's disease, and celiac disease without the need to increase ...
Ernest Asamoah
doaj   +1 more source

Addison's disease and ACTH-producing pituitary microadenoma

Revista Médica del Hospital General de México, 2015
A 28-year-old man diagnosed with primary adrenal insufficiency (Addison's disease) in 2002. Following diagnosis, replacement therapy with hydrocortisone and fludrocortisone was indicated. Hydrocortisone replacement therapy was unsuccessful, and increased
S.S. Ortega, Y.H. Aguiar, P.P. Marrero, S.M. Casas   +3 more
doaj   +1 more source

Global consensus on the management of melanin hyperpigmentation disorders

Journal of the European Academy of Dermatology and Venereology, EarlyView.
A global Delphi consensus of 10 dermatology experts established evidence‐based recommendations for melanin hyperpigmentation disorders, providing unified classification, photoprotection guidance and treatment algorithms. This framework harmonizes terminology and supports individualized management across diverse skin types and health systems.
Thierry Passeron, Seemal R. Desai, Marwa Abdallah, Firas Al‐Niaimi, Ncoza Dlova, Pearl E. Grimes, Jorge Ocampo‐Candiani, Rashmi Sarkar, Leihong Flora Xiang, Helio Amante Miot   +9 more
wiley   +1 more source

Pre-hospital management of acute Addison’s Disease – Audit of patients attending a referral hospital in a regional area [PDF]

, 2019
Context: Adrenal crises (AC) cause morbidity and mortality in patients with Addison’s disease [primary adrenal insufficiency (PAI)]. Patient-initiated oral stress dosing, with parenteral hydrocortisone, is recommended to avert ACs. While these should be
Goubar, Thomas, McGrath, Shaun, Rushworth, R Louise, Torpy, David J   +3 more
core   +1 more source

Autoimmune Polyglandular Syndrome Type 2: An Unusual Presentation

Acta Medica Iranica, 2010
Autoimmune polyglandular syndrome (APS) type 2 is characterized by the presence of Addison's disease, in association with autoimmune thyroid disease and/or type 1 diabetes mellitus.
Hamdollah Karamifar, Satila Dalili, Zohreh Karamizadeh, Gholamhosein Amirhakimi, Hosein Dalili   +4 more
doaj  

The effect of genetic bottlenecks and inbreeding on the incidence of two major autoimmune diseases in standard poodles, sebaceous adenitis and Addison’s disease

Canine Genetics and Epidemiology, 2015
BackgroundSebaceous adenitis (SA) and Addison’s disease (AD) increased rapidly in incidence among Standard Poodles after the mid-twentieth century.
N. Pedersen, Lynn Brucker, N. Tessier, Hongwei Liu, M. Penedo, S. Hughes, A. Oberbauer, B. Sacks   +7 more
semanticscholar   +1 more source

Limited musculoskeletal benefits of artificial gravity combined with cycling during bed rest: Results from the BRACE study

Experimental Physiology, EarlyView.
Abstract Prolonged exposure to microgravity, simulated via 6° head‐down tilt bed rest (HDT), induces musculoskeletal deconditioning and negatively impacts body composition. This study evaluated whether a combination of aerobic exercise with artificial gravity (AG) offers superior protection in comparison to exercise alone.
Mirko Mandić, Tommy R. Lundberg, Jean‐Pol Frippiat, Adam C. McDonnell, Igor B. Mekjavić, Marie‐Pierre Bareille, Rebecca Billette de Villemeur, Rodrigo Fernandez‐Gonzalo   +7 more
wiley   +1 more source

Sheehan's syndrome (postpartum hypopituitarism), report of a case [PDF]

, 1962
A case of postpartum necrosis of the anterior lobe of the pituitary, known as Sheehan's syndrome, is presented. The patient has done well on a combined replacement therapy with cortisone and thyroid.
Kibata, Masayoshi, Miyoshi, Isao
core   +1 more source