Results 91 to 100 of about 1,227,271 (311)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
, 2014 In Australia, children with additional needs are now primarily educated in mainstream regular classes and schools. While discussion has focused on teacher attitudes, teacher preparation and professional development to support the academic progress of ...
McDonagh, Sarah H. +2 more
core
Value of flexible electric vehicles in providing spinning reserve services [PDF]
, 2015 peer reviewedAs the share of integrated renewable energy sources (RES) increases, traditional operation principles of the power systems need to change in order to maintain reliable and secure service provision, on one hand, and minimal cost and ...
Kuzle, Igor +2 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Awareness, attitudes, and perceptions of regular education students towards students who receive special education services in their classes [PDF]
, 2004 Plan BThe purpose of this study was to investigate, determine, and analyze the awareness, attitudes, and perceptions of sixth through eighth grade students receiving regular education services toward the students receiving special education services in ...
Johnson, Sarah A.
core
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Open Access Complements Interlibrary Loan Services, but Additional User Education is
Evidence Based Library and Information Practice, 2016 Objective – To examine interlibrary loan (ILL) request rates for open access (OA) materials and determine how OA may affect resource sharing. This research updates the author’s previous study. Design – Quantitative analysis.
Richard Hayman
doaj
A Cost-Benefit Analysis of Additive Manufacturing as a Service
Proceedings of the 15th International Conference on Cloud Computing and Services ScienceIn Proceedings of the 15th International Conference on Cloud Computing and Services Science (CLOSER 2025).
Igor Ivkic +2 more
openaire +2 more sources