Results 61 to 70 of about 11,513,807 (298)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

METHOD OF PRIZES DETERMINE ON ADDITIONAL SERVICES WHICH ARE AVAILABLE FOR PASSENGERS IN RAILWAY STATIONS AND TRAINS

open access: yesNauka ta progres transportu, 2011
The order of drafting of calculations on the additional services given to passengers at train stations is considered; a procedure of calculation of the direct charges is offered.
H. S. Piatyhorets
doaj  

Comparison of Worst Pattern of Invasion with Other Histopathological Prognostic Indicators in Oral Cavity Squamous Cell Carcinoma: A Cohort Study from Regional Cancer Centre, Thiruvananthapuram, Kerala, India

open access: yesNational Journal of Laboratory Medicine
Introduction: Oral Cavity Squamous Cell Carcinoma (OCSCC) is one of the most common cancers worldwide and a leading cause of morbidity and mortality in certain parts of the world like South-Central Asia.
KR Anila   +4 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Methodical approach to determination of price for services of train stations taking into account seasonal coefficients to optimize prices depending on demand

open access: yesNauka ta progres transportu, 2012
The author offers the method of determination of price for services of the train stations, which takes into account a seasonal coefficient that allows optimizing a price depending on demand on these services.
G.S. Piatygorets
doaj  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Assessing youth-friendly sexual and reproductive health services: a systematic review

open access: yesBMC Health Services Research, 2018
BackgroundOver the last quarter century, there has been an emergence of evidence-based research directed toward the development, implementation, and assessment of youth-friendly health services (YFHS) to improve the delivery of sexual and reproductive ...
A. Mazur, C. Brindis, Martha J. Decker
semanticscholar   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Healthcare services gap analysis: a supply capture and demand forecast modelling, Dubai 2018–2030

open access: yesBMC Health Services Research, 2023
Background Health systems aim to provide a range of services to meet the growing demand of Dubai's heathcare system aims to provide a range of services to meet the growing demand of its population health needs and to ensure that standards of easy access,
Nahed Monsef   +3 more
doaj   +1 more source

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