Results 111 to 120 of about 1,035,528 (296)

Uniform Bahadur Representation for LocalPolynomial Estimates of M-Regressionand Its Application to The Additive Model [PDF]

open access: yes
We use local polynomial fitting to estimate the nonparametric M-regression function for strongly mixing stationary processes {(Y_i,?X_i ) } . We establish a strong uniform consistency rate for the Bahadur representation of estimators of the regression ...
Yingcun Xia, Oliver Linton, Efang Kong
core  

Limiting travel speed in additive layer manufacturing [PDF]

open access: yes, 2013
Wire and Arc Additive Manufacture (WAAM) is new approache to modern manufacturing. This technology has been gaining the interest of the research community due to its high deposition rate and efficiency. In Wire and Arc Additive Manufacture an increase in
Adebayo, Adeyinka   +2 more
core   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Nonparametric estimation of an additive model with a link function [PDF]

open access: yes
This paper describes an estimator of the additive components of a nonparametric additive model with a known link function. When the additive components are twice continuously differentiable, the estimator is asymptotically normally distributed with a ...
Enno Mammen, Joel Horowitz
core  

Physics-Aligned Data Augmentation for Reliable Property Prediction in Direct Ink Writing Under Extreme Data Scarcity

open access: yesJournal of Manufacturing and Materials Processing
Reliable property prediction in extrusion-based additive manufacturing remains challenging under extreme data scarcity (e.g., sample size of
Biva Gyawali   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Efficient Estimation of an Additive Quantile Regression Model [PDF]

open access: yes
In this paper two kernel-based nonparametric estimators are proposed for estimating the components of an additive quantile regression model. The first estimator is a computationally convenient approach which can be viewed as a viable alternative to the ...
Zerom, Dawit   +2 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Dominance of capacities by k-additive belief functions [PDF]

open access: yes
In this paper we deal with the set of $k$-additive belieffunctions dominating a given capacity. We follow the lineintroduced by Chateauneuf and Jaffray for dominating probabilities and continued by Grabisch for general $k$-additive measures.First, we ...
Michel Grabisch   +2 more
core  

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