Results 71 to 80 of about 1,035,528 (296)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Updating Choquet Integrals , Consequentialism and Dynamic Consistency [PDF]
Choquet capacities have been used to represent decision makers’ beliefs in order to generalise the expected utility approach. Conditional capacities have to be defined for dynamic choice situations where information may modify the decision maker future ...
André Lapied +2 more
core
additive: Bindings for Additive TidyModels
Fit Generalized Additive Models (GAM) using 'mgcv' with 'parsnip'/'tidymodels' via 'additive' . 'tidymodels' is a collection of packages for machine learning; see Kuhn and Wickham (2020) ). The technical details of 'mgcv' are described in Wood (2017) .To
Badr, Hamada S.
core +1 more source
The paper addresses the group decision-making (GDM) problem involving hesitant-intuitionistic fuzzy preference relations (HIFPRs), focusing on additive consistency and group consensus analysis.
Xue Feng, Sheng Ling Geng, Yong Ming Li
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Inconsistency and non-additive Choquet integration in the Analytic Hierarchy Process [PDF]
We propose to extend the aggregation scheme of Saaty’s AHP, from the stan- dard weighted averaging to the more general Choquet integration. In our model, a measure of inconsistency between criteria is derived from the main pairwise comparison matrix and ...
Ricardo Alberto Marques Pereira +1 more
core
Soil moisture (SM) remote sensing is widely used for agricultural drought monitoring, yet most applications still emphasize static moisture states rather than event-scale wetting responses.
Pingfan Fu +10 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Consistency of the proposed additive measures of revealed comparative advantage [PDF]
The recently proposed additive measures of revealed comparative advantage (RCA) have been argued as better alternatives to the Balassa Index. This note builds on those suggestions and provides a framework to assess their applicability by means of their ...
Ufuk gunes Bebek
core
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

