Results 141 to 150 of about 4,477,780 (283)

INITIAL AND BOUNDARY VALUE PROBLEMS FOR DIFFERENCE EQUATIONS [PDF]

open access: yes
We consider initial and boundary value problems for linear nonhomogeneous difference equations with constant coefficients. For such problems we compute the numerical values of the solutions using the discrete deconvolution.
Mircea I CÎRNU
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Periodic solutions of whole line difference equations,

open access: yes, 2004
Periodicity of the solutions of whole line difference equations is investigated. The considered equations is linear and of convolution type.
Russo E, Vecchio A, Crisci MR
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Linearizable Exact and Explicit Analytic Solutions for Riccati Differential Equations

open access: yes
In this paper, linearizable exact and explicit analytic solutions for classical Riccati differential equations are investigated in the complex field C by locally reducing the equations to other q-difference-differential equations and constructing ...
Jianguo Si, Linli Liu
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Additional file 1 of The clinical impact of estimating low-density lipoprotein cholesterol (LDL-C) using different equations in the general population

open access: yes
Additional file 1: Table S1. Comparison of LDL-C estimated by the Friedewald and Martin-Hopkins Equations for those participants with triglycerides < 400 mg/dL and further stratified by triglycerides < 175 and 175 < 400 mg/dL, count (%). Table S2.
Lam, Reyna   +13 more
openaire   +1 more source

Home - About - Disclaimer - Privacy