Results 171 to 180 of about 4,477,780 (283)

A Practical Identifiability Criterion Leveraging Weak-Form Parameter Estimation. [PDF]

Bull Math Biol
Heitzman-Breen N, Dukic V, Bortz DM.
europepmc   +1 more source

Equilibrium and bifurcation analysis of a stochastic logistic difference equation with additive noise

Discrete and Continuous Dynamical Systems - S
Yang Yang, Xiaoling Han
openaire   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Trigger Point Electrical Dry Needling with Different Waveforms for Knee Osteoarthritis: Mechanistic Insights and Methodological Considerations [Letter]. [PDF]

J Pain Res
Yu Y, Zhang H, Hu X, Liu Y, Zhang M, Zhang C, Wang L.   +6 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Functionally graded thermoelectric materials/devices: a review on experimental techniques and computational modelling for performance improvement. [PDF]

RSC Adv
Rai S, Tewari A, Gupta A.
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Magnesium Sulfate as an Analgesic and Sedative-sparing Agent in Patients under Mechanical Ventilation: A Randomized, Double Blind Clinical Trial. [PDF]

J Res Pharm Pract
Yaryari AM, Khalili H, Ramezani M, Ghazi SF, Mohammadi M.   +4 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Investigation on the Fatigue and Rutting Behavior of Asphalt Binder Containing Compound Warm Mixing Agent. [PDF]

Materials (Basel)
Fu Q, Chang T, Yang Q, Zhang N, Huang Z, Yu K, Li Q.   +6 more
europepmc   +1 more source