Results 91 to 100 of about 373,315 (309)
Nonparametric estimation of an additive model with a link function [PDF]
This paper describes an estimator of the additive components of a nonparametric additive model with a known link function. When the additive components are twice continuously differentiable, the estimator is asymptotically normally distributed with a ...
Enno Mammen, Joel Horowitz
core
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Modified Criterion for Economic Efficiency Estimation of Heat Pumps
Chemical Engineering Transactions, 2013 In this work the cost-effectiveness of coal mine waste water low potential heat utilization and integration in the enterprise local heating network by the bivalent parallel scheme is investigated.
S. Boldyryev +6 more
doaj +1 more source
Boosting Additive Models using Component-wise P-Splines [PDF]
, 2007 We consider an efficient approximation of Bühlmann & Yu’s L2Boosting algorithm with component-wise smoothing splines. Smoothing spline base-learners are replaced by P-spline base-learners which yield similar prediction errors but are more advantageous ...
Hothorn, Torsten, Schmid, Matthias
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
On a Conjecture of Kátai for Additive Functions
Journal of Number Theory, 1996 Let \(|x|\) denote the distance of \(x\) from the nearest integer and \(\Delta\) the forward difference of an arithmetic function \(f: \Delta f(n)= f(n+ 1)- f(n)\). The authors give two proofs of Kátai's conjecture: if \(f: \mathbb{N}\to \mathbb{R}\) is additive and \((*)\) \(|\Delta f(n)|\to 0\), then there exists \(\tau\in \mathbb{R}\) such that ...
Wirsing, Eduard +2 more
openaire +1 more source
Nonparametric estimation of an additive quantile regression model [PDF]
This paper is concerned with estimating the additive components of a nonparametric additive quantile regression model. We develop an estimator that is asymptotically normally distributed with a rate of convergence in probability of n-r/(2r+1) when the ...
Sokbae 'Simon' Lee, Joel Horowitz
core
Flexible semiparametric mixed models [PDF]
, 2005 In linear mixed models the influence of covariates is restricted to a strictly parametric form. With the rise of semi- and nonparametric regression also the mixed model has been expanded to allow for additive predictors.
Reithinger, Florian, Tutz, Gerhard
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source