Results 111 to 120 of about 735,575 (281)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Some Reverse Inequalities for Scalar Birkhoff Weak Integrable Functions
The Minkowski and Hölder inequalities play an important role in many areas of pure and applied mathematics, such as Convex Analysis, Probabilities, Control Theory, Fixed Point theorems, and Mathematical Economics.
Anca Croitoru +3 more
doaj +1 more source
Let 0 ⩽e < 1 and letX, Y be real normed spaces. In this paper we consider the following functional inequality:∥f(x + y) − f(x) − f(y)∥ ⩽ e min{∥f(x + y)∥, ∥f(x) + f(y)∥} forx, y ∈ R, wheref: X → Y. Mainly continuous solutions are investigated. In the case whereY = R some necessary and some sufficient conditions for this inequality are given.
openaire +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Hyers–Ulam Stability of Solution for Generalized Lie Bracket of Derivations
In this work, we present a new concept of additive-Jensen s-functional equations, where s is a constant complex number with ...
Vahid Keshavarz, Mohammad Taghi Heydari
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source

