Results 141 to 150 of about 79,677 (309)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Process Mapping for Qualification Across Multiple Direct Metal Additive Manufacturing Processes

open access: yes, 2013
This paper gives an overview of work by the authors developing process mapping methods for additive manufacturing (AM), capturing the dependence of melt pool geometry and microstructure on primary processing variables under steady-state and transient ...
Montgomery, Colt   +10 more
core   +1 more source

On subadditive functions and ψ-additive mappings

open access: yesOpen Mathematics, 2003
Abstract In [4], assuming among others subadditivity and submultiplicavity of a function ψ: [0, ∞)→[0, ∞), the authors proved a Hyers-Ulam type stability theorem for “ψ-additive” mappings of a normed space into a normed space. In this note we show that the assumed conditions of the function ψ imply that ψ=0 and, consequently, every “ψ ...
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Genetic analysis and candidate gene mining of flowering time in cucumber under low-light stress

open access: yesVegetable Research
Low-light stress significantly impacts the growth and yield of cucumber (Cucumis sativus L.), making it essential to comprehensively understand the genetic mechanisms governing flowering time adaptation.
Kaihong Hu   +6 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Use of Artificial Intelligence in Design, Development, Additive Manufacturing, and Certification of Multifunctional Composites for Aircraft, Drones, and Spacecraft

open access: yes
Multifunctional composites provide more than one function from the same part. The anisotropy, material, and process characterization challenges and the lack of standardization on the 3D-printed multifunctional carbon composites make it difficult for ...
Asokan Raji, Ritesh Ghimire
core   +1 more source

The influence of mid-ocean ridges on euphausiid and pelagic ecology

open access: yes, 2012
Chapters 1 & 2. Euphausiids comprise a major component of ecosystems in the pelagic realm, the world’s largest habitat, but basin scale drivers of euphausiids diversity and abundance are poorly understood. Mid-Ocean Ridges are the largest topographical
Letessier, Tom Bech
core   +1 more source

Bifurcations of the Hénon Map with Additive Bounded Noise

open access: yesSIAM Journal on Applied Dynamical Systems
We numerically study bifurcations of attractors of the Hénon map with additive bounded noise with spherical reach. The bifurcations are analysed using a finite-dimensional boundary map. We distinguish between two types of bifurcations: topological bifurcations and boundary bifurcations.
Jeroen S. W. Lamb   +2 more
openaire   +2 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

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