Results 191 to 200 of about 79,677 (309)

On orthogonally additive functions with big graphs

, 2018
Let E be a separable real inner product space of dimension at least 2 and V be a metrizable and separable linear topological space. We show that the set of all orthogonally additive functions mapping E into V and having big graphs is dense in the space ...
Baron, Karol
core  

Multi-trait GWAS of reaction norm parameters reveals environment-responsive loci influencing reproductive performance in heifers. [PDF]

J Anim Sci Biotechnol
Mota LFM, Arikawa LM, Santos DJA, Brito LF, Fonseca LFS, Oliveira HN, Albuquerque LG.   +6 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Audiovisual integration in reading among school-aged children: Evidence from combined fMRI and EEG. [PDF]

Dev Cogn Neurosci
Ren J, Wang H, Landi N, Joanisse MF, Gracco V, Kleinman D, Mahaffy K, Bajracharya A, Hancock R, Pugh K, Hoeft F.   +10 more
europepmc   +1 more source

Extensions of additive mappings [PDF]

Czechoslovak Mathematical Journal, 1965
openaire   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Genetic architecture of angular leaf spot resistance in cultivated strawberry shaped by epistasis and genotype-by-environment interactions. [PDF]

Plant Genome
Torgeman S, Pincot DDA, Bjornson M, Famula RA, Skillin P, Krill-Brown A, Feldmann MJ.   +6 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Semantic Algorithmic Information Theory: From Kolmogorov Complexity to Semantic Equivalence. [PDF]

Entropy (Basel)
Wu J, Wang S, Niu K, She Y, Zhang P.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source