Results 141 to 150 of about 127,524 (304)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Geometric Benchmarking of Metal Material Extrusion Technology: A Preliminary Study
Applied SciencesMetal additive manufacturing technologies such as powder bed fusion (PBF) and direct energy deposition (DED) are experiencing fast development, due to the growing awareness of industries.
Gabriele Locatelli +3 more
doaj +1 more source
Stretch maps on the affine-additive group
We define linear and radial stretch maps in the affine-additive group, and prove that they are minimizers of the mean quasiconformal distortion functional.
Balogh, Z. M., Platis, I. D., Bubani, E.
core
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Bifurcations of the Hénon Map with Additive Bounded Noise
SIAM Journal on Applied Dynamical SystemsWe numerically study bifurcations of attractors of the Hénon map with additive bounded noise with spherical reach. The bifurcations are analysed using a finite-dimensional boundary map. We distinguish between two types of bifurcations: topological bifurcations and boundary bifurcations.
Jeroen S. W. Lamb +2 more
openaire +2 more sources
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
Ring isomorphisms and linear or additive maps preserving zero products on nest algebras
, 2004 It is shown that every ring isomorphism between norm closed standard subalgebras of nest algebras acting on infinite dimensional Banach spaces is either a spatial isomorphism or a spatial conjugate isomorphism.
Hou, Jinchuan, Zhang, Xiuling
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Additive maps derivable or Jordan derivable at zero point on nest algebras
, 2010 Let AlgN be a nest algebra associated with the nest N on a (real or complex) Banach space X. Assume that every N∈N is complemented whenever N-=N. Let δ:AlgN→AlgN be an additive map. It is shown that the following three conditions are equivalent: (1) δ is
Hou, Jinchuan +3 more
core +1 more source