Results 111 to 120 of about 425,584 (289)

Composite Cyclotomic Fourier Transforms with Reduced Complexities

, 2010
Discrete Fourier transforms~(DFTs) over finite fields have widespread applications in digital communication and storage systems. Hence, reducing the computational complexities of DFTs is of great significance.
Chen, Ning, Wagh, Meghanad, Wang, Ying, Wu, Xuebin, Yan, Zhiyuan   +4 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

In Situ Formation of a Metastable β-Ti Alloy by Laser Powder Bed Fusion (L-PBF) of Vanadium and Iron Modified Ti-6Al-4V

Metals, 2018
The aim of this work is to investigate the β-Ti-phase-stabilizing effect of vanadium and iron added to Ti-6Al-4V powder by means of heterogeneous powder mixtures and in situ alloy-formation during laser powder bed fusion (L-PBF).
Florian Huber, Thomas Papke, Christian Scheitler, Lukas Hanrieder, Marion Merklein, Michael Schmidt   +5 more
doaj   +1 more source

The Influence of the Material Structure on the Mechanical Properties of Geopolymer Composites Reinforced with Short Fibers Obtained with Additive Technologies. [PDF]

Int J Mol Sci, 2022
Korniejenko K, Kejzlar P, Louda P.
europepmc   +1 more source

Towards Fully Additively-Manufactured Permanent Magnet Synchronous Machines: Opportunities and Challenges [PDF]

, 2019
With the growing interest in electrification and as hybrid and pure electric powertrains are adopted in more applications, electrical machine design is facing challenges in terms of meeting very demanding performance metrics for example high specific ...
EL-Refaie, Ayman M., Wu, Fan
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Fatigue response of as built DMLS processed Maraging Steel and effects of machining and heat and surface treatments [PDF]

, 2018
The main motivations for this study arise from the need for an assessment of the fatigue performance of DMLS produced Maraging Steel MS1, when it is used in the \u201cas fabricated\u201d state. The literature indicates a lack of knowledge from this point
Bogojevic, Nebojsa, Ciric-Kostic, Snezana, Croccolo, Dario, De Agostinis, Massimiliano, Fini, Stefano, Muharemovic, Nusret, Olmi, Giorgio, Robusto, Francesco, Vranic, Aleksandar   +8 more
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Achieving high strength and ductility in Inconel 718: tailoring grain structure through micron-sized carbide additives in PBF-LB/M additive manufacturing

Virtual and Physical Prototyping
Few attempts have been made so far to develop modifiers for in situ use in Inconel 718 PBF-LB/M fabrication. Reports show an increase in tensile strength compared to unmodified counterparts.
Konrad Gruber, Wojciech Stopyra, Karol Kobiela, Philipp Kohlwes, Jan Čapek, Efthymios Polatidis, Ingomar Kelbassa   +6 more
doaj   +1 more source