Kinesin‐Induced Buckling Reveals the Limits of Microtubule Self‐Repair
Advanced Science, EarlyView.This study shows that kinesin‐driven buckling induces extensive microtubule lattice damage that often exceeds intrinsic self‐repair and leads to filament failure. While curvature, motor motility, and force individually cause limited damage, their combination overwhelms repair.
Shweta Nandakumar +9 more
wiley +1 more source
A Practical Identifiability Criterion Leveraging Weak-Form Parameter Estimation. [PDF]
Bull Math BiolHeitzman-Breen N, Dukic V, Bortz DM.
europepmc +1 more source
Advanced Science, EarlyView.This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang +10 more
wiley +1 more source
Dynamic Analysis of Bi-Stable Galloping Energy Harvesters Under Random Excitation. [PDF]
Micromachines (Basel)Zhang Y, Qin R, Zheng K, Zhang J.
europepmc +1 more source
Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease
Advanced Science, EarlyView.This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang +15 more
wiley +1 more source
Vibration-based bearing fault diagnosis in noisy conditions using matrix pencil mean frequency and multilayer perceptron neural networks. [PDF]
PLoS OneLaib A +6 more
europepmc +1 more source
Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES
Advanced Science, EarlyView.In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu +5 more
wiley +1 more source
Closed-Form Approximations of Range Mutual Information for Integrated Sensing and Communication Systems. [PDF]
Sensors (Basel)Lai Z, Luo H, Wang Y, Zhang Y, Jin B.
europepmc +1 more source
Energy‐Resolved Femtosecond Dynamics of Plasmon‐Induced Hole Injection at Au/GaN Heterointerfaces
Advanced Science, EarlyView.We reveal the spectral signature of ultrafast nonthermal hot‐hole transfer at plasmonic heterointerfaces, which reshapes hot‐carrier relaxation dynamics and significantly enhances hydrogen evolution, providing a mechanistic basis for optimizing hot‐carrier utilization in photocatalysis.
Yuying Gao +8 more
wiley +1 more source
Self-secure feedback control based scheme for ultra-reliable and low-latency communication. [PDF]
PLoS OneYang Z, Wang X, Lu S, Wang J, Yuan H.
europepmc +1 more source