Results 41 to 50 of about 12,996,285 (285)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
“Wish me Health, Kalmyk!” (The Issues of the Textual Aspect, the Materials to the Comments: Part II)
The article discusses some textual aspects of the known by now reconstructions of the early (draft) edition of A.S. Pushkin's address to the Literature and Theatre Society “Green Lamp” (texts dated back to the beginning of 1821 and no later than spring ...
B. Kichikova
doaj
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Autobituary: the Life and/as Death of David Bowie & the Specters from Mourning
This article addresses the uncanny fascination for specters that long haunted David Bowie’s artistry. Following the hauntological work of Jacques Derrida and a few of his followers, I consider the ways in which the late Bowie came to haunt the late Bowie,
Jake Cowan
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Fractal sets satisfying the strong open set condition in complete metric spaces [PDF]
Let \(K\) be a Hutchinson fractal in a complete metric space \(X\), invariant under the action \(S\) of the union of a finite number of Lipschitz contractions. The Open Set Condition states that \(X\) has a non-empty subinvariant bounded open subset \(V\)
Gerald S. Goodman
doaj
Piecing together the maternal death puzzle through narratives: the three delays model revisited. [PDF]
BACKGROUND: In Malawi maternal mortality continues to be a major public health challenge. Going beyond the numbers to form a more complete view of why women die is critical to improving access to and quality of emergency obstetric care.
Viva Combs Thorsen +2 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Microwave photonic sensor systems represent a wide class of information systems with measurement conversion that use standardized analog and parallel links of parallel and sequential type with filtering, allowing to functionally displaying the ...
A.Zh. Sakhabutdinov, O.G. Morozov
doaj
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source

