Results 131 to 140 of about 7,378 (310)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Herbal remedies in written communication: The interpretation of the message [PDF]

open access: yes, 2012
[Abstract] For ages, herbal medicine was the part of community or family oral tradition. Transmitted through generations, the knowledge of medicinal use of plants is often described as kept secretly, within defined group of initiated.
Söukand, Renata
core  

RESPONSE TO ADDRESS OF WELCOME AND PRESIDENTʼS ADDRESS [PDF]

open access: yesAJN, American Journal of Nursing, 1913
n ...
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Peculiarities And Means of Pragmatic Functions Realization in Speech Genre “Oath” in Russian And English Communication

open access: yesВестник Волгоградского государственного университета: Серия 2. Языкознание, 2015
The article is devoted to presenting some characteristics of pragmatic functions in textual realizations of the speech genre "Oath" and describes peculiarities and language means of the identifying, performative, inspirational, declarative, integrative ...
Zarina Nailevna Sirazieva
doaj   +1 more source

Opening Address [PDF]

open access: yesProceedings of the Royal Society of Edinburgh, 1878
n ...
openaire   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Direct discourse expressing evidential values in Catalan Sign Language [PDF]

open access: yes, 2017
This paper presents the unmarked grammatical and discursive means of expressing evidential values in Catalan Sign Language (LSC), an almost unexplored area in the signed language literature.
Jarque, Maria Josep, Pascual, Esther
core  

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