Results 341 to 350 of about 301,764 (392)
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Toxicology, 1995
Application of methods for the measurement of DNA and protein adducts in environmental studies was surveyed. The methods included the 32P-postlabelling assay, immunoassay and synchronous fluorescence spectroscopy for DNA adducts. Additionally, methods for detecting excreted urinary RNA and DNA adducts were discussed.
Aage Haugen +2 more
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Application of methods for the measurement of DNA and protein adducts in environmental studies was surveyed. The methods included the 32P-postlabelling assay, immunoassay and synchronous fluorescence spectroscopy for DNA adducts. Additionally, methods for detecting excreted urinary RNA and DNA adducts were discussed.
Aage Haugen +2 more
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Aerodynamic, Acoustic, and Vibratory Comparison of Arytenoid Adduction and Adduction Arytenopexy
The Laryngoscope, 2008AbstractHypothesis: Adduction arytenopexy (AP) with thyroplasty provides improved physiologic placement of the vocal fold and therefore provides improved acoustic, aerodynamic, and vibratory function as compared with arytenoid adduction (AA) with thyroplasty.Methods: Five cadaveric human larynges were prepared by removing supraglottic tissues and ...
Justin P. McNamar +3 more
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Adduction Contracture of the Thumb
New England Journal of Medicine, 1956ADDUCTION contracture of the thumb presents a most serious disability of the hand. The thumb is useless as an opponent for the fingers, is unable to abduct and rotate and, in some cases, blocks flexion of the fingers. The hand is incapable of proper grasp, pinch and stereognosis. The proper mechanics of position of the thumb are crippled.
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Heterogeneity in adducted thumbs sequence
American Journal of Medical Genetics, 1997We report on a boy with adducted thumbs, microcephaly, swallowing difficulties, hypotonia, and severe mental retardation, but without craniostenosis or arthrogryposis. An MRI scan showed myelinization according to age and mild ventricular enlargement.
Cyril Legum +4 more
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Acetaldehyde Adducts of Phospholipids
Alcoholism: Clinical and Experimental Research, 1982Incubation of rat liver microsomes with acetaldehyde followed by reduction with borohydride of the Schiff bases formed leads to the formation of the N‐ethyl derivatives of phosphatidylethanolamine and phosphatidylserine. Proof for this structure came from a comparison of these microsomal derivatives, and the nitrogenous bases derived therefrom by acid
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Redox reactions of hydrogen adducts of thymine: Comparisons with the reactions of hydroxyl adducts
Talanta, 1995Hydrogen atoms form two kinds of adducts with thymine (oxidizing and reducing). Redox reactions of these two kinds, popularly known as 5-hydrogenated-6-thyminyl (reducing) and 6-hydrogenated-5-thyminyl (oxidizing), were investigated where ferric ions (oxidizing) and ferrous ions (reducing) were used as the corresponding redox partners.
S. N. Bhattacharyya +2 more
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Adduction of catechol estrogens to nucleosides
Steroids, 2002We report the formation, detection, quantitation and structural characterization of products resulting from the adduction of deoxynucleosides (deoxyadenosine, deoxyguanosine, deoxycytidine and 5-methyldeoxycytidine) to the catechol estrogens (CE) of estrone, estradiol-17beta and estradiol-17 alpha. The crude products are obtained in a one-pot synthesis
Jouanin, Isabelle +4 more
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A Persistent 1,2‐Dihydrophosphasilene Adduct
Angewandte Chemie International Edition, 2015AbstractThe reaction of the arylchlorosilylene–NHC adduct ArSi(NHC)Cl [Ar=2,6‐Trip2‐C6H3; NHC=(MeC)2(NMe)2C] 1 with one molar equiv of LiPH2.dme (dme=1,2‐dimethoxyethane) affords the first 1,2‐dihydrophosphasilene adduct 2 (ArSi(NHC)(H)PH). The latter is labile in solution and can undergo head‐to‐tail dimerization to give [ArSi(H)PH]2 3 and “free” NHC.
Tibor Szilvási +4 more
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Endogenous Glutathione Adducts
Current Drug Metabolism, 2006This review provides an overview of the formation, pharmacology, and toxicology of endogenous glutathione (GSH)-adducts with particular emphasis on GSH-adducts that arise from lipid peroxidation. GSH is the major low-molecular-weight thiol in mammalian cells.
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Mercapturic Acids, Protein Adducts, and DNA Adducts as Biomarkers of Electrophilic Chemicals
Critical Reviews in Toxicology, 1992The possibilities and limitations of using mercapturic acids and protein and DNA adducts for the assessment of internal and effective doses of electrophilic chemicals are reviewed. Electrophilic chemicals may be considered as potential mutagens and/or carcinogens.
R. T. H. van Welie +3 more
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