Results 251 to 260 of about 123,381 (324)
Cas9‐Embedding Hyperactive TadA8e Confers Efficient and Highly Specific A‐To‐G Base Editing in Rice
ABSTRACT Adenine base editors (ABEs) produce precise A‐to‐G conversion in the genomic target sites without causing double‐strand breaks. However, the hyperactive adenosine deaminase TadA8e raises safety concerns on genome‐wide off‐target edits. We engineered 11 chimeric proteins for ABEs (CP‐ABEs) by embedding hyperactive TadA8e within Cas9 nickase to ...
Jianjian Hu +14 more
wiley +1 more source
High tide or low tide: the transport and metabolism of mitochondrial nucleotides. [PDF]
MacVicar T.
europepmc +1 more source
ABSTRACT Mango (Mangifera indica) is one of the most popular fruits cultivated in tropical and subtropical regions of the world. The availability of reference genomes helps to identify the genetic basis of important traits. Here, we report assembled high‐quality chromosome‐level genomes for the Australian mango cultivar ‘Kensington Pride’ and M ...
Upendra Kumari Wijesundara +5 more
wiley +1 more source
Base Editing‐Mediated Targeted Evolution of Populus CesA8 Boosts Cellulose Production
Plant Biotechnology Journal, EarlyView.
Xinrui Jia +4 more
wiley +1 more source
ABSTRACT Sea Island cotton (Gossypium barbadense) produces premium‐quality fibres, yet the genetic basis underlying its fibre development remains elusive. Here, we identify two key non‐synonymous single nucleotide polymorphisms (SNPs, G/C and G/A) in the gene Gbar_D13G024080, which encodes the TRANSMEMBRANE PROTEIN 209 (TMEM209). These SNPs resulted in
Kaiyun Jiang +25 more
wiley +1 more source
A Small Cationic Probe for Accurate, Punctate Discovery of RNA Tertiary Structure. [PDF]
Ehrhardt JE +6 more
europepmc +1 more source
ABSTRACT Pokkah Boeng disease (PBD), caused by Fusarium sacchari, has severely impacted the yield and quality of sugarcane, resulting in significant economic losses. However, the molecular interaction mechanisms between F. sacchari and sugarcane remain poorly understood.
Deng Wu +8 more
wiley +1 more source
ABSTRACT Xanthomonas oryzae pv. oryzae (Xoo) is the causal agent of bacterial leaf blight (BLB) disease in rice, exerting a detrimental impact on the yield of various rice cultivars in Vietnam, notably the Bacthom 7 (BT7) variety. Xoo possesses transcription activator‐like effectors (TALEs) which modulate the expression of host genes by specifically ...
Nguyen Duy Phuong +8 more
wiley +1 more source
Alterations in Adenylate Nucleotide Metabolism and Associated Lipid Peroxidation and Protein Oxidative Damage in Rat Kidneys Under Combined Acetaminophen Toxicity and Protein Deficiency. [PDF]
Voloshchuk OM +4 more
europepmc +1 more source

