Results 271 to 280 of about 117,318 (358)

Development of CD73 Inhibitors in Tumor Immunotherapy and Opportunities in Imaging and Combination Therapy. [PDF]

J Med Chem
Bi C, Patel JS, Liang SH.
europepmc   +1 more source

Stabilization of the catalytically active structure of a molybdenum‐dependent formate dehydrogenase depends on a highly conserved lysine residue

The FEBS Journal, EarlyView.
Molybdenum‐dependent formate dehydrogenases (Mo‐FDHs) contain a strictly conserved lysine residue (K44) in the vicinity of an electron‐transferring [4Fe‐4S] cluster and a catalytically active molybdenum atom coordinated by two molybdopterins (MPT‐1 and MPT‐2).
Feilong Li, Michael Lienemann
wiley   +1 more source

The role of respiration metabolism in dicyclohexylcarbodiimide and disodium succinate regulating the pulp breakdown occurrence of fresh longan (<i>Dimocarpus longan</i> Lour.) during storage. [PDF]

Food Chem X
Zheng Y, Lin Y, Wen H, Sang Y, Lin M, Fan Z, Wang H, Chen Y, Lin Y, Lin H.   +9 more
europepmc   +1 more source

A steric gate prevents mutagenic dATP incorporation opposite 8‐oxo‐deoxyguanosine in mitochondrial DNA polymerases

The FEBS Journal, EarlyView.
Reactive oxygen species induce mutagenic DNA lesions, such as 8‐oxo‐2′‐deoxyguanosine (8‐oxodG), which acts as a template for dCMP and dAMP incorporation through its anti and syn conformations. Specific residues must regulate the fidelity of templated 8‐oxodG.
Noe Baruch‐Torres, Carlos H. Trasviña‐Arenas, Alexandru Ionut Gilea, Upeksha C. Dissanayake, Missael Molina‐Jiménez, Paola L. García‐Medel, Corina Díaz‐Quezada, Tiziana Lodi, G. Andrés Cisneros, Enrico Baruffini, Luis G. Brieba   +10 more
wiley   +1 more source

Highly selective DNA aptamer sensor for intracellular detection of coenzyme A. [PDF]

Chem Sci
Ma Y, Lewis W, Yan P, Shao X, Mou Q, Kong L, Guo W, Lu Y.   +7 more
europepmc   +1 more source

Tentoxin-induced energy-independent adenine nucleotide exchange and ATPase activity with chloroplast coupling factor 1.

, 1978
S. Reimer, Bruce R. Selman
openalex   +1 more source

Y12C mutation disrupts IMPDH cytoophidia and alters cancer metabolism

The FEBS Journal, EarlyView.
IMPDH, the rate‐limiting enzyme for de novo GTP synthesis, can form polymers and cytoophidia to enhance activity by reducing GTP inhibition. In this study, a Y12C mutation in IMPDH2 was introduced via ABEmax base‐editing in human cancer cell lines to disrupt IMPDH polymerisation.
Chia‐Chun Chang, Min Peng, Gerson Dierley Keppeke, Li‐Kuang Tsai, Ziheng Zhang, Li‐Mei Pai, Li‐Ying Sung, Ji‐Long Liu   +7 more
wiley   +1 more source

Probing the Coupled Equilibria between Metal Nanoparticles, Antibiotics and Components of the Extracellular Matrix in Biofilms with SERS. [PDF]

Biomacromolecules
Aljuhani W, Wylie MP, Purusottam RN, McCoy CP, Bell SEJ.   +4 more
europepmc   +1 more source

Atrial Fibrillation (AF) and Heart Failure With Preserved Ejection Fraction (HFpEF): Advances and Challenges

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT This state‐of‐the‐art review is based on the Philippe Coumel Lecture in 2024 (Figure 1). It highlights the confluence of two major cardiovascular epidemics, atrial fibrillation and heart failure, with preserved ejection fraction. In these conditions, advances in electrophysiology and heart failure physiology are intertwined and are integrated ...
Sanjeev Saksena, April Slee, Ranghadham Nagarakanti, Atul Prakash   +3 more
wiley   +1 more source

Synthesis of Adenine Nucleosides with a Reactive (<i>β</i>-Iodovinyl)sulfone or (<i>β</i>-Keto)sulfone Group at the C2 Position and Their Polymerase-Catalyzed Incorporation into DNA. [PDF]

Molecules
Howlader AH, Fernandez R, Tsegay PS, Liu Y, Wnuk SF.   +4 more
europepmc   +1 more source