Results 291 to 300 of about 1,279,856 (386)

Prognostic and immunological profiling of SEC61G in cervical squamous cell carcinoma and adenocarcinoma. [PDF]

Discov Oncol
Ye Y, Song L, Zhang J, Liu S, Han S.
europepmc   +1 more source

Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

Cell, 2012
M. Imieliński, A. Berger, P. Hammerman, Bryan Hernandez, Trevor J Pugh, Eran Hodis, Jeonghee Cho, J. Suh, M. Capelletti, A. Sivachenko, C. Sougnez, D. Auclair, M. Lawrence, P. Stojanov, K. Cibulskis, Kyusam Choi, L. D. Waal, Tanaz Sharifnia, Angela N. Brooks, H. Greulich, S. Banerji, T. Zander, D. Seidel, F. Leenders, S. Ansén, C. Ludwig, W. Engel‐Riedel, E. Stoelben, J. Wolf, C. Goparju, K. Thompson, W. Winckler, D. Kwiatkowski, B. Johnson, P. Jänne, V. Miller, W. Pao, W. Travis, H. Pass, S. Gabriel, E. Lander, Roman K. Thomas, L. Garraway, G. Getz, M. Meyerson   +44 more
semanticscholar   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

GEJ Adenocarcinoma Following Antireflux Surgery: A Missed Diagnosis. [PDF]

ACG Case Rep J
Son C, Ansari M, Ceesay S, Kalapala J, Loh J, Zhang H.   +5 more
europepmc   +1 more source

CSN6 Promotes Pancreatic Cancer Progression and Gemcitabine Resistance via Antagonizing DCAF1‐Mediated Ubiquitination of NPM1

Advanced Science, EarlyView.
COP9 signalosome subunit 6 (CSN6) promotes the auto‐ubiquitination and degradation of DDB1‐CUL4 associated factor 1 (DCAF1), thereby antagonizing DCAF1‐mediated ubiquitination of Nucleophosmin (NPM1). This stabilization of NPM1 enhances the ribosome biogenesis process and the translation of specific gemcitabine‐resistance proteins, ultimately driving ...
Yijing Zhang, Han Gao, Aiwen Tang, Haiwen Lyu, Zongmin Fan, Jiahui Guo, Yuzhi Wang, Hairong Yi, Qihao Pan, Haidan Luo, Baifu Qin, Boyu Zhang, Xiangqi Meng, Qingxin Liu, Mong‐Hong Lee   +14 more
wiley   +1 more source

Clinicopathological features and prognosis of patients with colorectal Mucinous adenocarcinoma mixed with other pathological components: a nationwide retrospective study in China. [PDF]

Tech Coloproctol
Yuan J, He H, Zhang P, Guan X, Yu M, Zhang Y, Ning S, Wang L, Lv Y, Jiao M, Sun Y, Sun Q, Ren X, Liu D, Zhang Z, Ye Z, Li J, Yu G, Ma B, Fu W, Kong XH, Jing C, Tao K, Sun Y, Jiang C, Chen J, Zhang G, Yang H.   +27 more
europepmc   +1 more source

A comparison of multimodal therapy and surgery for esophageal adenocarcinoma.

New England Journal of Medicine, 1996
T. Walsh, N. Noonan, D. Hollywood, A. Kelly, N. Keeling, T. Hennessy   +5 more
semanticscholar   +1 more source

Positive Feedback Loop of Histone Lactylation‐Driven HNRNPC Promotes Autophagy to Confer Pancreatic Ductal Adenocarcinoma Gemcitabine Resistance

Advanced Science, EarlyView.
Histone 3 lysine18 lactylation (H3K18la) drives heterogeneous nuclear ribonucleoprotein C (HNRNPC) overexpression, activating autophagy to mediate gemcitabine resistance by stabilizing TNF receptor‐associated factor 6 (TRAF6) mRNA. Concurrently, HNRNPC stabilizes aldehyde dehydrogenase 1 family member A3 (ALDH1A3) mRNA, which enhances glycolysis and ...
Xi‐Tai Huang, Jiao Chen, En‐Liang Zhu, Ming‐Jian Ma, Yang‐Yin‐Hui Yu, Ying‐Qin Zhu, Jing‐Yuan Ye, Jin‐Zhao Xie, Zi‐Yi Zhao, Xiao‐Yu Yin   +9 more
wiley   +1 more source

Anti-Müllerian hormone plays a bidirectional role in cancer: a multi-database and multi-method study. [PDF]

Discov Oncol
Wang Y, Xi Z, Peng Y, Gao Y, Guo X, Qu G, Wang Z, Peng H.   +7 more
europepmc   +1 more source

MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma.

Journal of the American Medical Association (JAMA), 2008
Aaron J. Schetter, S. Leung, Jane J. Sohn, Krista A. Zanetti, E. Bowman, N. Yanaihara, S. Yuen, T. Chan, D. Kwong, G. Au, Chang-gong Liu, G. Calin, C. Croce, C. Harris   +13 more
semanticscholar   +1 more source