Results 91 to 100 of about 32,072 (264)

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

open access: yesInternational Journal of Cancer, Volume 158, Issue 6, Page 1617-1627, 15 March 2026.
What's new? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman   +15 more
wiley   +1 more source

Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design

open access: yesImmunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Ilka Grewe   +2 more
wiley   +1 more source

Clinical and Cephalometric Assessments in Grade II and Grade IV Adenoid Hypertrophy: A Cross-Sectional Study

open access: yesمجلة كلية الطب
Background: Adenoid hypertrophy is one of the most common causes of nasal obstruction, and physicians use different methods to investigate it to reach a definite diagnosis.
Afnan R. Razaq, Hayder F. Saloom
doaj   +1 more source

Awake ECMO for Mid‐Tracheal Obstruction: When a Tracheostomy Isn't Enough

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Awake VV‐ECMO can be a life‐saving strategy for patients with near‐complete tracheal obstruction where tracheostomy and intubation are not feasible. Early multidisciplinary coordination enables safe airway control, tumor debulking, and stenting, facilitating both immediate stabilization and long‐term oncologic planning.
Jacob Beiriger   +8 more
wiley   +1 more source

Pleural Metastasis From Male Breast Cancer: A Case Report

open access: yesDiagnostic Cytopathology, Volume 54, Issue 2, Page E36-E39, February 2026.
ABSTRACT Male breast cancer (MBC) is a rare disease accounting for less than 1% of breast cancers and for 0.11% of all male malignancies. Despite the fact that the epidemiologic, clinical, and therapeutic literature regarding female breast cancer is well documented, little is known about the features of male breast cancer.
Patrizia Straccia, Esther Diana Rossi
wiley   +1 more source

Multiparametric Ultrasound for Preoperative Assessment of Parotid Tumors: A Novel Diagnostic Pathway

open access: yesHead &Neck, Volume 48, Issue 2, Page 392-406, February 2026.
ABSTRACT Background Accurate preoperative differentiation of parotid gland tumors (PGTs) is essential for facial nerve preservation. This study evaluates a novel, real‐time multiparametric ultrasound (mpUS) approach combining B‐mode, shear wave elastography (SWE), and contrast‐enhanced ultrasound (CEUS), based on qualitative image interpretation ...
Katharina Margherita Wakonig   +5 more
wiley   +1 more source

Efektivitas Terapi Kortikosteroid Intranasal pada Hipertrofi Adenoid Usia Dewasa berdasarkan Pemeriksaan Narrow Band Imaging

open access: yesMajalah Kedokteran Bandung, 2016
Adenoid hypertrophy is a process in which adenoid size becomes enlarged and causes clinical symptoms, especially nasal obstruction. Adenoid hypertrophy can be due to physiological, inflammatory, or malignancy processes.
Sinta Sari Ratunanda   +4 more
doaj  

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