Results 31 to 40 of about 32,072 (264)

Safety and Efficacy of Adoptive Transfer of Stem Cell Memory Enriched Virus Specific T Cells against CMV and EBV

Advanced Science, EarlyView.
This study finds that CD8⁺ TSCM cells exhibit superior self‐renewal, differentiation, and antiviral activity. Transcriptome and epigenome analyses highlight MAPK cascade regulation in TSCM cells. In vivo, virus‐specific TSCM cells show enhanced persistence and tumor protection.
Xun‐Hong Cao, Xu‐Ying Pei, Yuan‐Yuan Zhang, Juan Xie, Jing‐Wei Tu, Zhuo‐Jun Liu, Yi‐Yang Ding, Chen‐Hua Yan, Yu‐Hong Chen, Yu Wang, Lan‐Ping Xu, Xiao‐Hui Zhang, Xiao‐Jun Huang, Xiang‐Yu Zhao   +13 more
wiley   +1 more source

CD20+FCRL4+ B Cells Activate CD8+ T Cells via MHC‐I Restriction in Nasopharyngeal Carcinoma Anti‐Tumor Immunity

Advanced Science, EarlyView.
CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang, Xiaotian Yuan, Kelei Gao, Bo You, Yaxuan Wang, Lai Meng, Zirong Chen, Shaobing Xie, Yunqing Liu, Zijian Dong, Shumin Xie, Ruohao Fan, Fengjun Wang, Junyi Zhang, Zhihai Xie, Yongzhen Mo, Hua Zhang, Weihong Jiang   +17 more
wiley   +1 more source

Carcinoma adenoide cístico / Adenoid cystic carcinoma

Brazilian Journal of Development, 2022
O carcinoma adenoide cístico (CAC) é a neoplasia maligna mais frequente das glândulas salivares menores, caracteriza-se clinicamente por ser de crescimento lento, a localização mais frequente é o palato duro. Objetivo: O objetivo do presente trabalho será discorrer sobre as principais características do CAC.
Raiane Ferreira de Paula, Luciana Estevam Simonato, Karina Gonzalez Camara Fernandes   +2 more
openaire   +1 more source

Mepylome: A Point‐of‐Care Tumor Diagnostic Toolkit for Tumor DNA Methylation and Copy Number Analysis

Advanced Intelligent Systems, EarlyView.
DNA methylation and chromosomal copy number profiling have recently become essential for tumor diagnostics. The open‐source tool Mepylome enables this task in clinical routine. It combines several machine learning strategies and allows users to interactively examine respective data through an intuitive graphical interface. Running up to 65 times faster
Jon Brugger, Claus Hultschig, Daniel Baumhoer, Baptiste Ameline, Benjamin Maciej Freyter, Stephan Frank, Jürgen Hench   +6 more
wiley   +1 more source

Performance Characteristics of Milan System for Reporting Salivary Gland Cytopathology: An Experience From Western Saudi Population

Diagnostic Cytopathology, EarlyView.
ABSTRACT Introduction Salivary gland tumors are rare but diverse, with a higher prevalence of benign tumors in the parotid gland and a greater incidence of malignancy in other glands. Fine needle aspiration (FNA), enhanced by the Milan Reporting System, is widely used to evaluate these tumors.
Samah Saharti, Reem Aljohani
wiley   +1 more source

Patterns of Cervical Metastases and Implications for Neck Management in Minor Salivary Gland Cancer Treatment

Head &Neck, EarlyView.
ABSTRACT Objectives Minor salivary gland cancer (MiSGC) is a rare and heterogeneous disease, with different degrees of tumor aggressiveness. The scarce data in the literature show that the presence of lymph node metastases (LNMs) negatively impacts the prognosis.
Eduardo Wanderley Estanislau da Costa, Pedro Nicolau‐Neto, Paula Moretz‐Sohn, Bernardo Cacciari Peryassu, Emilson de Queiroz Freitas, Luis Felipe Ribeiro Pinto, Fernando Luiz Dias   +6 more
wiley   +1 more source

Effectiveness of Evaluation of Adenoid Hypertrophy in Children by Flexible Nasopharyngoscopy Examination (FNE), Proposed Schema of Frequency of Examination: Cohort Study

Diagnostics, 2022
Objectives: To demonstrate the effectiveness of endoscopic assessment of the pharyngeal tonsil in defining the size of the adenoid hypertrophy in endoscopic examination that would be equivalent to intraoperative assessment as a large adenoid, and to ...
Aleksander Zwierz, Krzysztof Domagalski, Krystyna Masna, Paweł Burduk   +3 more
doaj   +1 more source

The Immunological Correlation With Adenoid Hypertrophy and Allergic Rhinitis in Children

iNew Medicine, EarlyView.
The imbalance of Th1/Th2 and Th17/Treg cells in allergen and inflammatory responses might be associated with the development of adenoid hypertrophy, suggesting that allergic rhinitis maybe the risk factor of AH and providing a potential alternative explanation for adenoid hypertrophy pathogenesis.
Yang Song, Chao Zhang, Jun Song, Jian‐Ming Yang, Wei Wei   +4 more
wiley   +1 more source

Patient and Caregiver Perception of Adenoidectomies: A Non‐Real‐World Social Media Analysis

OTO Open
Objective To survey the social media outlets Twitter and Instagram for public posts related to adenoidectomy surgery. This study aims to investigate the attitudes and perceptions of patients and caregivers on social media, through thematic content ...
Nikhil B. Godbole, Ethan D. Paliwoda, Avi A. Gajjar, Nithin Gupta, Alexander Nguyen, Andrew Nguyen, Richard Alexander   +6 more
doaj   +1 more source

Adenoiditis

, 2010
Synonyms: Nasopharyngitis, coryza. Definition: Acute manifestation of an initially afebrile catarrhal (predominantly viral) infection of the mucosa of the nasopharynx, adenoids and mostly also of the nose.
Ganzer, Uwe, Arnold, Andreas
openaire   +1 more source