Results 41 to 50 of about 66,574 (336)

An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma

Nature Genetics, 2016
Translocation events are frequent in cancer and may create chimeric fusions or 'regulatory rearrangements' that drive oncogene overexpression. Here we identify super-enhancer translocations that drive overexpression of the oncogenic transcription factor ...
Y. Drier, M. J. Cotton, Kaylyn E. Williamson, Shawn M. Gillespie, Russell J. H. Ryan, Michael J. Kluk, Christopher D. Carey, S. Rodig, L. Sholl, A. Afrogheh, W. Faquin, L. Queimado, J. Qi, M. Wick, A. El-Naggar, J. Bradner, C. Moskaluk, J. Aster, B. Knoechel, B. Bernstein   +19 more
semanticscholar   +1 more source

Primary cutaneous adenoid cystic carcinoma with lung metastasis: A case report with literature review

Radiology Case Reports
Adenoid cystic carcinoma is a rare tumor that typically originates from secretory glands, most commonly found in the salivary glands. However, it can also develop as a primary cutaneous adenoid cystic carcinoma, which appears identical under the ...
Fatima Zahrae El Mansoury, DR, Ola Messaoud, DR, Hatim Essaber, DR, Soukaina Allioui, DR, Assaad El Bakkari, DR, Hounayda Jerguigue, DR, Youssef Omor, PR, Rachida Latib, PR, Samia Sassi, DR, Fouad Zouaidia, PR   +9 more
doaj   +1 more source

C-kit expression in the salivary gland neoplasms adenoid cystic carcinoma, polymorphous low-grade adenocarcinoma, and monomorphic adenoma [PDF]

, 2003
Objective. Differentiating between adenoid cystic carcinomas (ACCs), polymorphous low-grade adenocarcinomas (PLGAs), and the monomorphic adenomas (including canalicular adenomas, trabecular adenomas, and basal cell adenomas) can present a diagnostic ...
Bhuiya, Tawfigul, Edwards, Paul C., Kelsch, Robert D   +2 more
core   +1 more source

Adenoid cystic carcinoma of the breast [PDF]

Postgraduate Medical Journal, 1983
Summary Adenoid cystic carcinoma is a rare malignant tumour of the breast. It usually presents as a painful, apparently benign lump near the nipple. The tumour has an interesting histology, natural history and mammographic appearance. Mastectomy is usually curative.
R. C. Smith, R. C. Jaworski, K. L. Kneale   +2 more
openaire   +3 more sources

Sex determining region Y-box 2 (SOX2) amplification is an independent indicator of disease recurrence in sinonasal cancer. [PDF]

, 2013
The transcription factor SOX2 (3q26.3-q27) is an embryonic stem cell factor contributing to the induction of pluripotency in terminally differentiated somatic cells.
Agaimy, Abbas, Bode, Maike, Bootz, Friedrich, Braun, Martin, Franzen, Alina, Göke, Friederike, Huss, Sebastian, Ihrler, Stephan, Kirsten, Robert, Kristiansen, Glen, Lengerke, Claudia, Menon, Ropika, Perner, Sven, Schröck, Andreas, Wagner, Patrick   +14 more
core   +3 more sources

MYB promotes the growth and metastasis of salivary adenoid cystic carcinoma

International Journal of Oncology, 2019
The incidence of recurrent t(6;9) translocation of the MYB proto-oncogene to NFIB (the gene that encodes nuclear factor 1 B-type) in adenoid cystic carcinoma (ACC) tumour tissues is high. However, MYB [the gene that encodes transcriptional activator Myb (
Li-Hua Xu, Fei Zhao, Wen-Wen Yang, Chu-Wen Chen, Z. Du, Min Fu, X. Ge, Sheng-lin Li   +7 more
semanticscholar   +1 more source

Evaluation of Bax In situ hybridization and PCNA Immunohistochemical Expression in Adenoid Cystic Carcinoma

Diyala Journal of Medicine, 2019
Background: Adenoid cystic carcinoma constitutes the second common malignant epithelial salivary gland tumour. Objective: To evaluate the expression of Bax mRNA and PCNA and to correlate between the clinicopathological features of Adenoid cystic ...
Lehadh Muhammed Al-Azzawi, Qutaiba Ali Hussain   +1 more
doaj   +2 more sources

Adenoid cystic carcinoma of cervix: two cases report and review of the litterature

The Pan African Medical Journal, 2015
Adenoid cystic carcinoma of the cervix is a rare and aggressive tumor with fatal outcome. In this paper we report two cases of primary adenoid cystic carcinoma and a review of literature. A 80 years old woman, admitted to our hospital with postmenopausal
Khadija Benhayoune, Hinde El Fatemi, Abdelaziz Bannani, Abdelilah Melhouf, Toufik Harmouch   +4 more
doaj   +1 more source

Metastasis of spine from adenoid cystic carcinoma of the parotid gland: two case reports 

Journal of Medical Case Reports, 2023
Background Spinal metastasis from adenoid cystic carcinoma of the salivary gland is extremely rare. We present two interesting cases of spinal metastasis from adenoid cystic carcinoma of the parotid gland. Case summary A 29-year-old Persian male and a 48-
Saeid Safaei, Parisa Azimi, Taravat Yazdanian   +2 more
doaj   +1 more source

Trigeminal nerve and pathologies in magnetic resonance imaging : a pictorial review [PDF]

, 2018
A variety of conditions may affect the trigeminal nerve. Magnetic resonance imaging is the modality of choice when trigeminal nerve pathology is suspected, and this modality plays an essential role in detecting causes. This review illustrates some of the
Akgoz, Ayca, Bulut, Elif, Gocmen, Rahsan, Gunes, Altan, Mocan, Burce, Oguz, Kader Karli   +5 more
core   +2 more sources