Results 81 to 90 of about 31,503 (264)

TP53 and p16INK4A, but not H-KI-Ras, are involved in tumorigenesis and progression of pleomorphic adenomas. [PDF]

, 2006
The putative role of TP53 and p16INK4A tumor suppressor genes and Ras oncogenes in the development and progression of salivary gland neoplasias was studied in 28 cases of pleomorphic adenomas (PA), 4 cases of cystic adenocarcinomas, and 1 case of ...
AGNESE, Valentina, AUGELLO, Claudia, BAZAN, Viviana, BRUNO, Loredana, CALO', Valentina, CAMMARERI, Patrizia, CASCIO, Sandra, CORSALE, S, GARGANO, G, GERBINO, Aldo, GREGORIO, Valter, GULLO, Arianna, MACALUSO, M, MORELLO, Vincenza, PASSANTINO, Rita, RINALDI, G, RUSSO, Antonio, SURMACZ, E, TOMASINO, Rosa Maria   +18 more
core   +1 more source

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

International Journal of Cancer, Volume 158, Issue 6, Page 1617-1627, 15 March 2026.
What's new? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman, Niven Mehra, Laurien J. Zeverijn, Birgit S. Geurts, Karlijn Verkerk, Soemeya F. Haj Mohammad, Vincent van der Noort, Paul Roepman, Wendy W. J. de Leng, Anne M. L. Jansen, Addy C. M. van de Luijtgaarden, Theo van Voorthuizen, Tineke E. Buffart, Hans Gelderblom, Emile E. Voest, Henk M. W. Verheul   +15 more
wiley   +1 more source

Review of salivary gland neoplasms [PDF]

, 2012
Salivary gland tumours most often present as painless enlarging masses.Most are located in the parotid glands andmost are benign. The principal hurdle in their management lies in the difficulty in distinguishing benign from malignant tumours ...
Chan, JYW, To, VSH, Tsang, RKY, Wei, WI
core   +1 more source

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

Advanced Healthcare Materials, Volume 15, Issue 10, 13 March 2026.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen, Jialin Li, Yan Wu, Han Bao, Xuesong Yang, Guoqing Lv, Ke Ji, Ji Zhang, Xiaojiang Wu, Kai Zhou, Jieli Xu, Jiatian Tang, Xiyuan Han, Anqiang Wang   +13 more
wiley   +1 more source

A report of laryngeal adenocystic carcinoma metastatic to the spleen and the role of splenectomy in the management of metastatic disease: a case report

Journal of Medical Case Reports, 2010
Introduction Adenoid cystic carcinoma (ACC) of the larynx is a rare malignancy characterized by an indolent course and late pulmonary metastases. Metastases from the larynx to the spleen are an unusual event.
Murray Bryce W, Lyons Lewis C, Mancino Anne T, Huerta Sergio   +3 more
doaj   +1 more source

Mepylome: A Point‐of‐Care Tumor Diagnostic Toolkit for Tumor DNA Methylation and Copy Number Analysis

Advanced Intelligent Systems, Volume 8, Issue 3, March 2026.
DNA methylation and chromosomal copy number profiling have recently become essential for tumor diagnostics. The open‐source tool Mepylome enables this task in clinical routine. It combines several machine learning strategies and allows users to interactively examine respective data through an intuitive graphical interface. Running up to 65 times faster
Jon Brugger, Claus Hultschig, Daniel Baumhoer, Baptiste Ameline, Benjamin Maciej Freyter, Stephan Frank, Jürgen Hench   +6 more
wiley   +1 more source

Smoking, Alcohol, and Their Interaction in the Risk of Head and Neck Cancer: A Nationwide Cohort Study

Cancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background Smoking and alcohol drinking are established causes of head and neck cancer (HNC), yet their combined effect and variation by anatomic sub‐site remain incompletely defined. Methods We followed 5,985,244 Korean adults (≥ 30 years) who attended National Health Insurance health screening in 2002–2003 until 31 December 2019.
Eunjung Park, Hee‐Yeon Kang, Yuh‐Seog Jung, Byungmi Kim, Thi Tra Bui, Jin‐Kyoung Oh   +5 more
wiley   +1 more source

Cytologic Characteristics of Adenoid Cystic Carcinoma of the Cervix Uteri – Case Report [PDF]

, 2010
Adenoid cystic carcinoma is a rare malignancy, usually found in the salivary glands, although this unusual tumor can be found at other sites of the body.
Ana Barišić, Ana Ovanin-Rakić, Damir Babić, Danijela Jurič, Lada Škopljanac-Mačina, Sanda Rajhvajn, Vesna Mahovlić   +6 more
core   +1 more source

Lesions mimicking lacrimal gland pleomorphic adenoma [PDF]

, 2010
Aim: To report a series of patients with lacrimal gland lesions simulating the clinicoradiological features of lacrimal gland pleomorphic adenoma (LGPA). Methods: Multicentre retrospective, interventional case series.
Cannon, P., Davis, G., Dolman, P., Ghabrial, R., McNab, A., O'Donnell, B., Prabhakaran, V., Selva-Nayagam, D.   +7 more
core   +1 more source

Adenoid Cystic Carcinoma of the Nasopharynx with Skull Base Involvement: Retrospective National Cohort Analysis of Treatment Paradigms, Outcomes, and Provider Density [PDF]

, 2020
Shekhar K. Gadkaree, Anuraag S. Parikh, Eric Barbarite, Allen L. Feng, Justin C. McCarty, Stacey T. Gray, Derrick T. Lin   +6 more
openalex   +1 more source