Results 61 to 70 of about 11,997 (295)

AKT, ATR, and Notch Inhibitors Radiosensitize a Preclinical Model of Adenoid Cystic Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Adenoid Cystic Carcinoma (ACC) is a rare and lethal type of head and neck cancer. Standard therapy involves surgery followed by radiation therapy. The majority of ACC has MYB overexpression and MYB‐NFIB gene fusions, while Notch mutations are associated with aggressive behavior.
Shivani Thoidingjam, Sushmitha Sriramulu, Asya Haider Muratoglu, Stephen Brown, Oudai Hassan, Benjamin Movsas, Haythem Ali, Steven Chang, Patrick Ha, Farzan Siddiqui, Shyam Nyati   +10 more
wiley   +1 more source

Unsupervised type III polygraphy in children undergoing adenotonsillectomy: a technical and economic report [PDF]

Sleep Science
Objective: To evaluate the economic and technical viability of the sleep study (type III) in children with adenotonsilar hypertrophy. Methods: 141 children were submitted to sleep study (type III), aged between three and 11, all with symptoms of ...
Iury Lima Veloso, Camila de Castro Corrêa, José Vicente Tagliarini, Silke Anna Theresa Weber   +3 more
doaj   +1 more source

Predominance of In‐Field Recurrence After Radiotherapy for Sinonasal Cancer: A Single‐Center Retrospective Study

Head &Neck, EarlyView.
ABSTRACT Background Sinonasal malignancies (SNM) are rare, heterogeneous tumors with poor prognosis. There is an unmet need to improve treatment outcomes. Despite advances in imaging and molecular classification, optimal curative radiotherapy (RT) strategies remain undefined.
M. de Ridder, L. J. van de Velde, T. de Bie, R. van Noortwijk, C. P. J. Raaijmakers, E. H. Voormolen, W. W. Braunius, R. de Bree, G. E. Breimer, L. A. Devriese, E. J. Smid, J. A. Rijken   +11 more
wiley   +1 more source

Respiração bucal em crianças com dificuldade de aprendizado

Brazilian Journal of Otorhinolaryngology, 2013
Devido à importância do estudo das causas de dificuldade de aprendizado, delineou-se estudo caso controle, para avaliar o volume das cavidades nasais, tonsilas faríngeas e tonsilas palatinas em crianças com e sem dificuldade de aprendizado. MÉTODO: Foram
Giovana Serrão Fensterseifer, Oswaldo Carpes, Luc Louis Maurice Weckx, Viviane Feller Martha   +3 more
doaj   +1 more source

Nasopharyngeal tonsils (adenoids) contain extrathymic corticothymocytes.

, 2014
Adenoidal tissue (also known as nasopharyngeal tonsils) of 58% of humans in the pediatric age group contains immature T-lymphoid cells with the phenotype of thymocytes (TdT+, CD1abc+, cytoplasmic CD3+, coexpressing CD4 and CD8, lacking an Intraepithelial
Fabio Pagni, Renato Maria Gaini, Giorgio Cattoretti, Werner Garavello, Serena Buscone   +4 more
core   +1 more source

Establishment of Salivary Gland Tumors Arising in Salivary Gland‐Specific EWSR1::ATF1 Transgenic Mice

Head &Neck, EarlyView.
ABSTRACT Background Salivary gland carcinomas are uncommon malignancies with various histological subtypes harboring fusion genes. The EWSR1::ATF1 fusion gene, resulting from a translocation between chromosomes 12 and 22, is frequently observed in hyalinizing clear cell carcinoma (HCCC). However, the role of this fusion gene in HCCC oncogenesis remains
Yuri Hirai, Yoshitaka Utsumi, Daisuke Sano, Tatsu Kuwahara, Yoshihiro Aizawa, Takashi Hatano, Hisashi Hasumi, Yutaro Soejima, Tatsukata Kawagoe, Ryosuke Jikuya, Nobuhisa Mizuki, Satoshi Fujii, Toshitaka Nagao, Nobuhiko Oridate   +13 more
wiley   +1 more source

A noisy airway: Varying causes for upper airway obstruction in a child

Current Medicine Research and Practice, 2023
Noisy breathing is a common symptom in infancy and childhood. It can sometimes be intimidating to the parents and a diagnostic challenge to the treating physician. Causes for a noisy airway include congenital and acquired conditions.
Ranjini Srinivasan, Sushma Krishna, Chitra Dinakar, C B Pratibha   +3 more
doaj   +1 more source

Systemic Treatments for Recurrent or Metastatic Sinonasal Carcinomas: A Retrospective Multicenter Study

Head &Neck, EarlyView.
ABSTRACT Introduction Sinonasal cancers are rare and heterogeneous and pose a therapeutic challenge at an advanced stage due to the lack of data on appropriate systemic management. Methods This retrospective multicenter study analyzed 83 patients with recurrent or metastatic sinonasal carcinomas ineligible for curative treatment, treated in France ...
Marie Degrange, Mathilde Morisseau, Justin Michel, Thibaut Reverdy, Sylvain Morinière, Amaury Daste, Maxime Humbert, Caroline Viala, Pauline Corbaux, Tiffany Darbas, François‐Régis Ferrand, Valentin Favier, Camille Evrard, Diane Evrard, Delphine Farneti, Sarah Betrian‐Lagarde, Victor Sarradin   +16 more
wiley   +1 more source

Clinicogenomic Features and Outcomes of Adenoid Cystic Carcinoma With Central Nervous System Metastases: A Single‐Institution Cohort Study

Head &Neck, EarlyView.
ABSTRACT Background Adenoid cystic carcinoma (ACC) is a rare malignancy with a propensity for perineural invasion and hematogenous spread. Central nervous system (CNS) involvement is uncommon, and detailed clinical and genomic data on this aspect of the disease remain limited.
Omar Elghawy, Jack Stylli, Martin Kurian, Eitan Halper‐Stromberg, Aditi Singh, Christopher D'Avella, Lee Hartner, Roger B. Cohen   +7 more
wiley   +1 more source

Automated diagnosis of adenoid hypertrophy with lateral cephalogram in children based on multi-scale local attention

Scientific Reports
Adenoid hypertrophy can lead to adenoidal mouth breathing, which can result in “adenoid face” and, in severe cases, can even lead to respiratory tract obstruction.
Yanying Rao, Qiuyun Zhang, Xiaowei Wang, Xiaoling Xue, Wenjing Ma, Lin Xu, Shuli Xing   +6 more
doaj   +1 more source