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Systematic review of prognostic factors in carcinoma ex pleomorphic adenoma.

Oral Oncology, 2022
OBJECTIVES Carcinoma ex Pleomorphic Adenoma (CXPA) is a rare primary salivary gland malignancy, typically arising from a pre-existing pleomorphic adenoma.
S. Key   +5 more
semanticscholar   +1 more source

HMGA2-WIF1 Rearrangements Characterize a Distinctive Subset of Salivary Pleomorphic Adenomas With Prominent Trabecular (Canalicular Adenoma-like) Morphology

American Journal of Surgical Pathology, 2021
Most of salivary gland neoplasms (benign and malignant) are characterized by recurrent gene fusions. Pleomorphic adenoma (PA), the most frequent salivary gland tumor, is driven by chromosomal rearrangements involving PLAG1 mapped to 8q12 and HMGA2 mapped
A. Agaimy   +8 more
semanticscholar   +1 more source

Pleomorphic adenoma: the great mimicker of malignancy

Histopathology, 2020
Pleomorphic adenoma (PA) is the most common salivary gland neoplasm, and its diagnosis is straightforward in the majority of cases. However, not infrequently, PA shows unusual and uncommon histological features that can be confused with those of ...
J. Hernandez-Prera   +7 more
semanticscholar   +1 more source

Natural history of recurrent pleomorphic adenoma: implications on management

Head and Neck, 2020
Treating recurrent pleomorphic adenoma (RPA) aims to reduce risk of malignant transformation (MT) while avoiding facial nerve injury. Our objective was to systematically investigate this natural history of RPA and address the current rational for its ...
M. Valstar   +3 more
semanticscholar   +1 more source

Risk factors for carcinoma ex pleomorphic adenoma in patients presenting with recurrence after resection of pleomorphic adenoma

Head and Neck, 2020
In patients presenting with recurrent pleomorphic adenoma (rPA), clinical evaluation can fail to recognize carcinoma ex PA (cxPA). We aim to identify the risk factors for cxPA.
L. Yin   +8 more
semanticscholar   +1 more source

Risk factors for subsequent recurrence after surgical treatment of recurrent pleomorphic adenoma of the parotid gland

Head and Neck, 2020
Recurrent pleomorphic adenoma (PA) can be a lifelong disease, and rates of subsequent recurrence are high.
Steven A Rooker   +8 more
semanticscholar   +1 more source

Tumour spillage of the pleomorphic adenoma of the parotid gland: A proposal for intraoperative measures.

Oral Oncology, 2020
Intraoperative rupture of a pleomorphic adenoma capsule with potential tumor spillage into the surgical field is thought to occur in approximately 5% of cases and has traditionally been recognized as one of the major causes of recurrence.
K. Mantsopoulos, H. Iro
semanticscholar   +1 more source

Recurrent pleomorphic adenoma

The Journal of Laryngology & Otology, 1993
Of 209 cases of pleomorphic adenoma treated in a 30 year period, 38 were secondary referrals with recurrent disease following surgery. Of these, 25 were women and 13 men with a mean time to recurrence of 9 years 4 months. Thirty-four recurrences were in the parotid gland.
S R, Jackson   +3 more
openaire   +2 more sources

Carcinoma ex pleomorphic adenoma: A review of incidence, demographics, risk factors, and survival.

American Journal of Otolaryngology, 2019
PURPOSE Identify variables that are independent predictors of survival in carcinoma ex pleomorphic adenoma (CXPA) of the major salivary glands using a population-based database and evaluate the incidence and management strategies for this rare malignancy.
Avigeet Gupta   +4 more
semanticscholar   +1 more source

Postoperative complications after removal of pleomorphic adenoma from the parotid gland: A long-term follow up of 297 patients from 2002 to 2016 and a review of publications.

British Journal of Oral and Maxillofacial Surgery, 2019
Pleomorphic adenomas are rounded, lumpy, capsulated lesions that are more common in women. They are typically benign, but can be associated with malignancy in a minority of cases (such as carcinoma ex pleomorphic adenoma), between 3% - 12% of the time ...
P. Bonavolontà   +8 more
semanticscholar   +1 more source

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