Results 101 to 110 of about 417,233 (389)

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Faecal haemoglobin and faecal calprotectin as indicators of bowel disease in patients presenting to primary care with bowel symptoms [PDF]

, 2015
OBJECTIVE: In primary care, assessing which patients with bowel symptoms harbour significant disease (cancer, higher-risk adenoma or IBD) is difficult.
Allison, Allison, Atkin, Callum G Fraser, Castro, Chiang, Craig Mowat, Cubiella, Duffy, Francis A Carey, Fraser, Fraser, Hazazi, Högberg, Jayne Digby, Jellema, Judith A Strachan, Kaul, Kok, Lieberman, McDonald, McDonald, NICE Diagnostics guidance (DG11), Parente, Pavlidis, Rapi, Robert J C Steele, Robyn Wilson, Roseth, Sipponen, Terhaar sive Droste, van Rheenen, Young   +32 more
core   +3 more sources

Patterns of Cervical Metastases and Implications for Neck Management in Minor Salivary Gland Cancer Treatment

Head &Neck, EarlyView.
ABSTRACT Objectives Minor salivary gland cancer (MiSGC) is a rare and heterogeneous disease, with different degrees of tumor aggressiveness. The scarce data in the literature show that the presence of lymph node metastases (LNMs) negatively impacts the prognosis.
Eduardo Wanderley Estanislau da Costa, Pedro Nicolau‐Neto, Paula Moretz‐Sohn, Bernardo Cacciari Peryassu, Emilson de Queiroz Freitas, Luis Felipe Ribeiro Pinto, Fernando Luiz Dias   +6 more
wiley   +1 more source

Very Long‐Term Follow‐Up of Multidimensional Health‐Related Quality of Life After Endoscopic Endonasal Surgery for Pituitary Adenomas: A Prospective Cohort Study

Head &Neck, EarlyView.
ABSTRACT Background To evaluate postoperative health‐related quality of life (HRQoL) for pituitary adenoma patients, multidimensional assessment is important. Available data is limited on long‐term follow‐up. Methods Prospectively, 52 nonfunctioning (NFA) and functioning (FA) pituitary adenoma patients were included.
Gonneke E. Joustra, Nathalie F. van Rhee, Marc C. den Heijer, Astrid G. W. Korsten‐Meijer, Robert A. Feijen, György B. Halmos, Jos M. A. Kuijlen, Karin M. Vermeulen   +7 more
wiley   +1 more source

Transanal minimally invasive surgery for rectal lesions [PDF]

, 2016
Background and Objectives: Transanal minimally invasive surgery (TAMIS) has emerged as an alternative to transanal endoscopic microsurgery (TEM). The authors report their experience with TAMIS for the treatment of mid and high rectal tumors.
Balla, Andrea, Di Lorenzo, Nicola, Franceschilli, Luana, Iafrate, Corrado, La Torre, Marco, Quaresima, Silvia, Shalaby, Mostafa, Sileri, Pierpaolo   +7 more
core   +1 more source

Dural arteriovenous fistula with isolated acute subdural hematoma

Asian Journal of Surgery, 2022
Jianguo Li, Cheng Chen, Peizhi Zhou
doaj   +1 more source

K-ras and p53 mutations in colonic lavage fluid of patients with colorectal neoplasias [PDF]

, 2001
Background: The adenoma-carcinoma sequence has its molecular basis in several gene mutations of which K-ras and p53 are of paramount importance. The aims of this study were to evaluate whether these genetic alterations can be detected in colonic lavage ...
Folwaczny, Christian, Heinzlmann, M., Heldwein, W., Neynaber, S.   +3 more
core   +1 more source

Indicators to identify cancer screening providers with suboptimal case detection: A scoping review

International Journal of Cancer, EarlyView.
What's New? Quality control of cancer screening programs is essential to maintaining high public health standards. Here, the authors reviewed monitoring of case detection in cervical and colorectal cancer screening programs in Europe, and evaluated its effectiveness. They analysed 20 different measures used for this purpose and showed that many of them
Jiayao Lei, Milena Falcaro, Adam R. Brentnall, James F. O'Mahony, Sisse Helle Njor, Matejka Rebolj   +5 more
wiley   +1 more source

Colorectal endoscopic submucosal dissection: patient selection and special considerations

Clinical and Experimental Gastroenterology, 2017
Andrew Emmanuel, Shraddha Gulati, Margaret Burt, Bu’Hussain Hayee, Amyn Haji King’s Institute of Therapeutic Endoscopy, King’s College Hospital, London, UK Abstract: Endoscopic submucosal dissection (ESD) enables en bloc resection of ...
Emmanuel A, Gulati S, Burt M, Hayee B, Haji A   +4 more
doaj  

Parathyroid localization [PDF]

, 1986
Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH.
Borisch, B., Gutekunst, R., Hafermann, W., Kiffner, E., Löhrs, U., Scriba, Peter Christian, Thies, E., Valesky, A.   +7 more
core   +1 more source