Results 161 to 170 of about 417,233 (389)

Cellular Stress, Inflammation and Barrier Damage in Gut Epithelial Cells Caused by Aspartame

open access: yesAllergy, EarlyView.
This study shows that aspartame, at dietary‐relevant doses, induces cytotoxicity, cellular distress associated with endoplasmic reticulum stress, oxidative stress, DNA replication and repair mechanism disturbance culminating in epithelial barrier damage.
Yagiz Pat   +16 more
wiley   +1 more source

Development and validation of a panel of five proteins as blood biomarkers for early detection of colorectal cancer

open access: yesClinical Epidemiology, 2017
Hongda Chen,1,2 Jing Qian,1 Simone Werner,1 Katarina Cuk,1 Phillip Knebel,3 Hermann Brenner1,4,5 1Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany; 2Program Office for Cancer Screening in ...
Chen H   +5 more
doaj  

International Guideline on the Diagnosis and Management of Pediatric Patients With Hereditary Angioedema

open access: yesAllergy, EarlyView.
ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas   +128 more
wiley   +1 more source

Histopathological and Immunohistochemical Characterization of Sebaceous Adenoma and Epithelioma in Dogs

open access: yesAnimals
Sebaceous gland tumors are neoplasms originating from the sebaceous gland and are the third most common type of skin tumor, accounting for 21–35% of all cutaneous neoplasms in dogs.
Sanggu Kim   +4 more
doaj   +1 more source

Pituitary Somatotroph Adenoma-derived Exosomes: Characterization of Nonhormonal Actions [PDF]

open access: bronze, 2021
Cuiqi Zhou   +5 more
openalex   +1 more source

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

open access: yesAndrology, EarlyView.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret   +5 more
wiley   +1 more source

β-Catenin Activated Hepatocellular Adenoma: A Report of Three Cases in Korea

open access: yesGut and Liver, 2014
Background/AimsUpregulated CD64 expression on neutrophils is the most useful marker for acute bacterial infections and systemic inflammation. However, it is unknown whether CD64 is involved in the pathogenesis of acute pancreatitis (AP).
doaj   +1 more source

Pituitary hyperplasia mimicking macroadenoma associated with primary hypothyroidism in a patient with selective L-thyroxine malabsorption [PDF]

open access: yes, 2017
We present the case of a 29-year-old woman who developed a severe hypothyroidism induced by a thyroxine malabsorption and a secondary pituitary hyperplasia.
Romanelli, Francesco   +4 more
core   +1 more source

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