Results 101 to 110 of about 19,562 (204)
Senescence‐Driven Remodeling Defines an Aggressive and Immunomodulatory Subtype of Endometriosis
Senescence in ectopic endometrial cells promotes SASP‐mediated M2 macrophage polarization and enhanced invasiveness of endometriotic lesions. PAK4 drives this process via PI3K/AKT signaling, while stigmasterol suppresses PAK4 and alleviates senescence‐associated immune remodeling. ABSTRACT Endometriosis is a benign yet invasive disease characterized by
Jingchun Liu +8 more
wiley +1 more source
Introduction Alterations in microbiota composition have been implicated in a variety of human diseases. Patients with adenomyosis present immune dysregulation leading to a persistent chronic inflammatory response.
Marta Valdés‐Bango +10 more
doaj +1 more source
The study of the role of genetic polymorphisms of cytokines in the hyperplastic uterogenic processes formation [PDF]
The aim of the study was to investigate the role of molecular-genetic markers of cytokines in the formation of hyperplastic processes in uterusyesБелгородский государственный ...
Altuhova, O. +4 more
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Three‐dimensional patient‐derived endometriosis model for drug evaluation
In this study, we developed a coculturing model with stromal cells and epithelial organoids to mimic the endometriotic lesion and for further evaluation of drug effects. Abstract Introduction Endometriomsis (EMs) is a complex and chronic gynecological disease characterized by distressing symptoms.
Yuqi Li +10 more
wiley +1 more source
Across studies, the percentage of individuals reporting regularly engaging in menstrual coitus ranges between 4% and 43%. Although no clinical guideline recommends avoiding sexual activity during menstruation, according to some researchers such practice ...
Giulia Emily Cetera +3 more
doaj +1 more source
Vitamin D Deficiency as an Independent Risk Factor for Adenomyosis: a Cross-Sectional Study
Background: The relationship between adenomyosis and vitamin D remains largely unexplored. However, emerging evidence suggests that vitamin D deficiency may increase the risk of developing adenomyosis.
Haijing Zhong +7 more
doaj +1 more source
Staging of endometrial cancer with MRI: Guidelines of the European Society of Urogenital Imaging [PDF]
The purpose of this study was to define guidelines for endometrial cancer staging with MRI. The technique included critical review and expert consensus of MRI protocols by the female imaging subcommittee of the European Society of Urogenital Radiology ...
Balleyguier, C. +9 more
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The “White line sign”: A novel sonographic soft marker of pelvic endometriosis
The “White line sign” represents thickening of the subperitoneal tissue overlying the anterior pouch of Douglas on transvaginal ultrasound. It demonstrated high specificity for detecting superficial endometriosis and high specificity, sensitivity, and accuracy for deep endometriosis. It was also reproducible and could be a useful soft ultrasound marker
Prubpreet Chaggar +4 more
wiley +1 more source
It is expected that the relugolix estetrol combination RE4W will enable women to control their fertility and prevent menstrual cycle related problems, while offering a smooth transition through perimenopause into the postmenopause and decrease the risk of breast cancer.
Herjan J. T. Coelingh Bennink +9 more
wiley +1 more source
Молекулярные основы этиопатогенеза и клиники эндометриоза [PDF]
Обзор литературы, освещающий современные вопросы этиологии и патогенеза ...
Пономаренко, И. В.
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