Results 371 to 380 of about 869,856 (392)
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Regulation of adenosine kinase by adenosine analogs.

Molecular Pharmacology, 1988
The regulation of adenosine phosphorylation by adenosine analogs was studied using highly purified human placental adenosine kinase [ATP: adenosine 5'-phosphotransferase (EC 2.7.1.20)]. Our observations lead us to classify the analogs into three groups as follows: type I, 5'-N-ethylcarboxamidoadenosine and 5'-methylthioadenosine; type II, N6 ...
B B, Lin, M C, Hurley, I H, Fox
openaire   +2 more sources

Immunohistochemistry of Adenosine Deaminase: Implications for Adenosine Neurotransmission

Science, 1984
Immunohistochemical analysis of adenosine deaminase in rat brain revealed an extensive plexus of adenosine deaminase-containing neurons in the basal hypothalamus. These neurons converged on and were most numerous in three major centers, namely, the tuberal, caudal, and postmammillary caudal magnocellular nuclei.
M. Buss   +3 more
openaire   +3 more sources

The adenosine pathway in immuno-oncology

Nature Reviews Clinical Oncology, 2020
B. Allard   +3 more
semanticscholar   +1 more source

Adenosine, adenosine receptors and glaucoma: An updated overview

Biochimica et Biophysica Acta (BBA) - General Subjects, 2013
Glaucoma, a leading cause of blindness worldwide, is an optic neuropathy commonly associated with elevated intraocular pressure (IOP). The major goals of glaucoma treatments are to lower IOP and protect retinal ganglion cells. It has been revealed recently that adenosine and adenosine receptors (ARs) have important roles in IOP modulation and ...
Wei Chieh Huang   +4 more
openaire   +3 more sources

Effect of adenosine deaminase on cardiac interstitial adenosine

American Journal of Physiology-Heart and Circulatory Physiology, 1992
Adenosine deaminase was infused into isolated perfused guinea pig hearts to determine its effect on myocardial adenosine levels. The enzyme was administered during constant coronary flow perfusion at 6.11 +/- 0.36 ml.min-1.g-1. Venous adenosine was measured in samples of pulmonary artery effluent; epicardial and endocardial adenosine were measured ...
Robert M. Berne   +4 more
openaire   +3 more sources

Adenosine Metabolism, Adenosine Kinase, and Evolution

2012
The enzyme adenosine kinase (AdK, ADK, or AK) plays an important role in regulating the intracellular as well as extracellular concentrations of adenosine and hence its diverse physiological actions. In view of the enormous pharmacological potential of adenosine, there has been much interest in studying adenosine kinase over the past few decades.
Jaoek Park, Radhey S. Gupta
openaire   +2 more sources

Adenosine, Adenosine Receptors and the Actions of Caffeine *

Pharmacology & Toxicology, 1995
Abstract:Of the known biochemical actions of caffeine, only inhibition of adenosine receptors occurs at concentrations achieved during normal human consumption of the drug. Under normal physiological conditions, adenosine is present in sufficient concentrations to activate A1and A2areceptors.
openaire   +2 more sources

International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors.

Pharmacological Reviews, 2001
B. Fredholm   +4 more
semanticscholar   +1 more source

Targeting immunosuppressive adenosine in cancer

Nature Reviews. Cancer, 2017
Dipti Vijayan   +3 more
semanticscholar   +1 more source

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