Results 121 to 130 of about 172,301 (236)

RETRACTED: Top 100 cited articles on anosmia and COVID‐19: A bibliometric analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView., 2023
Abstract Objectives With the exponential growth of literature on coronavirus disease 2019 (COVID‐19), we undertook a bibliometric analysis of the top 100 most cited COVID‐19‐related articles in anosmia, to identify high‐impact studies relating to anosmia as a symptom of early COVID‐19 infection.
Denise Jia Yun Tan, Tsz Ki Ko
wiley   +1 more source

Enhancing Adeno‐Associated Virus 2 Capsid Engineering Through Co‐Evolutionary Coupling

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated virus (AAV) has emerged as a leading platform for gene therapy. However, to unlock the full potential, their manufacturing yields, stability, and efficacy must all be improved. Rational design is limited by poor predictability and the potential impact of mutations on multiple important vector properties.
Sirimar Laosinwattana, Yiwen Li, Braulio Carrillo Sanchez, Ayesha Khan, Paul A. Dalby   +4 more
wiley   +1 more source

GAPDH suppresses adenovirus-induced oxidative stress and enables a superfast production of recombinant adenovirus

Genes and Diseases
Recombinant adenovirus (rAdV) is a commonly used vector system for gene transfer. Efficient initial packaging and subsequent production of rAdV remains time-consuming and labor-intensive, possibly attributable to rAdV infection-associated oxidative ...
Guozhi Zhao, Piao Zhao, Yonghui Wang, Hui Zhang, Yi Zhu, Jiamin Zhong, Wulin You, Guowei Shen, Changqi Luo, Ou Mei, Xingye Wu, Jingjing Li, Yi Shu, Hongwei Wang, William Wagstaff, Hue H. Luu, Yang Bi, Lewis L. Shi, Russell R. Reid, Tong-Chuan He, Li Jiang, Wei Tang, Jiaming Fan, Ziwei Tang   +23 more
doaj   +1 more source

Detection of adenovirus, respiratory syncytial virus and parainfluenza virus infections in our region in the 1995-96 winter season by cell culture method

, 1999
Bu çalışmada, solunum sistemi hastalıklarının önemli etkenlerinden olan solunum sinsityal virüsü, adenovirüs ve parainfluenza virüslerinin bölgemizdeki dağılımı ve sıklığı araştırılmıştır.
Serter, Demir, Dereli, Gökengin Deniz, Yamazhan, Tansu, Ertem, Ekin   +3 more
core  

Cell and Gene Therapies Manufacturing Challenges and Integrated Good Manufacturing Practices Solutions: A Lifecycle Perspective

Biotechnology and Bioengineering, EarlyView.
Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga, Udisha Singh, Sachin Dattram Pawar   +2 more
wiley   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Demonstration of nanofiltration‐based virus safety for AAV manufacturing using model viruses

Biotechnology Progress, EarlyView.
Abstract Virus safety for biopharmaceutical products has been a well‐established concern for several decades. While various virus reduction steps have been identified and implemented for traditional plasma‐derived and monoclonal antibody products, there are various challenges to achieving the same virus safety in emerging gene therapy products.
Brian Buesing, Tomoki Igi, Daniel Strauss   +2 more
wiley   +1 more source

Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed, Supreet S. Randhawa, Jason H. Peragallo, Prabhumallikarjun Patil, Grace Gombolay, Varun Kannan   +5 more
wiley   +1 more source

Capturing and concentrating adenovirus using magnetic anionic nanobeads

International Journal of Nanomedicine, 2016
Akikazu Sakudo,1 Koichi Baba,2 Kazuyoshi Ikuta1,31Department of Virology, Research Institute for Microbial Diseases, Osaka University, Yamadaoka, Suita, Osaka, Japan; 2Baba Pediatric Clinic, Kadoma, Osaka, Japan; 3Kanonji Institute, The Research ...
Sakudo A, Baba K, Ikuta K
doaj  

Detection of respiratory viruses in infants with acute bronchiolitis

, 2002
Bu çalışmada, akut bronşiyolit tanısı alan bebeklerde Solunum Sinsityal Virüs (RSV), Adenovirüs, influenza A ve B, Parainfluenza 1, 2, 3 antijenleri araştırılarak etiyolojik tanı amaçlanmıştır.
Tijen Özacar, Nuran Çetin, Süphan Özyurt, İmre Altuğlu, Altınay Bilgiç, Esra Özer   +5 more
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