Results 171 to 180 of about 113,140 (295)

A Multiple‐Model‐Informed Drug‐Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 572-582, March 2025.
ABSTRACT The antitumor efficacy of an intratumoral injection of a genetically engineered oncolytic vaccinia virus carrying human IL‐7 and murine IL‐12 genes (hIL‐7/mIL‐12‐VV) was demonstrated in CT26.WT‐bearing mice. In the CT26.WT‐bearing mouse model, the efficacy of the combination of hIL‐7/mIL‐12‐VV plus the anti‐programmed cell death protein (PD)‐1
Akihiro Yamada, Mary P. Choules, Frances A. Brightman, Shigeru Takeshita, Shinsuke Nakao, Nobuaki Amino, Takeshi Nakayama, Masato Takeuchi, Kanji Komatsu, Fernando Ortega, Hitesh Mistry, David Orrell, Christophe Chassagnole, Peter L. Bonate   +13 more
wiley   +1 more source

Severe Disseminated Adenovirus Infection After Haploidentical Hematopoietic Stem Cell Transplantation: A Case Report. [PDF]

Am J Case Rep
Yang DT, Hasan N, Chinchilla DB, Blodget E.   +3 more
europepmc   +1 more source

Human Adenovirus Infection Causing Hyperinflammatory Syndrome Mimicking Multisystem Inflammatory Syndrome in Children (MIS-C): A Case Report. [PDF]

Cureus, 2023
Diwakar K, Sarangi T, Srivastava P, Tanti SK, Swaroop S.   +4 more
europepmc   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Investigating the impact of the COVID-19 pandemic on pediatric adenovirus infection patterns: a retrospective analysis. [PDF]

Microbiol Spectr
Gu Y, Zhang X, Yan L, Wang Y, Hua S.
europepmc   +1 more source

Parotid enlargement due to adenovirus infection in patient with human immunodeficiency virus infection [PDF]

, 1996
Maria Irma Seixas Duarte, Valdir Sabbaga Amato, Juliane Gomes de Paula, David Éverson Uip, Marcos Boulos, Vicente Amato Neto   +5 more
openalex   +1 more source

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source

Treating Adenovirus Infection in Transplant Populations: Therapeutic Options Beyond Cidofovir? [PDF]

Viruses
Narsana N, Ha D, Ho DY.
europepmc   +1 more source

Adenovirus Infection in Pediatric Hematopoietic Cell Transplantation: A Challenge Still Open for Survival. [PDF]

J Clin Med, 2022
Cesaro S, Porta F.
europepmc   +1 more source

The epidemiology of adenovirus infections in Greater Manchester, UK 1982–96 [PDF]

, 2000
Robert J. Cooper, Rachel Hallett, A B Tullo, Paul E. Klapper   +3 more
openalex   +1 more source