Results 231 to 240 of about 115,226 (275)
CDK12 Inactivation Attenuates Prostate Cancer Progression by Inhibiting BNIP3‐Mediated Mitophagy
Cell Proliferation, Volume 59, Issue 2, February 2026.In response to enzalutamide, damaged mitochondria are targeted for mitophagic degradation through the binding of BNIP3 to LC3, forming autophagosomes that are subsequently transported to lysosomes for degradation. These self‐protective mechanisms promote mitochondrial renewal, reduce oxidative stress and finally contribute to cancer cell survival ...
Mengjun Huang +13 more
wiley +1 more source
Cell Proliferation, Volume 59, Issue 2, February 2026.The pathogenic mechanisms of pulmonary vascular endothelial cells (VECs) in lung diseases and their multimodal therapeutic strategies. ABSTRACT Pulmonary vascular endothelial cells (VECs) are essential for the normal function of the lung, through maintaining vascular barrier integrity, regulating blood flow, and participating in inflammatory responses ...
Qianyue Liu +5 more
wiley +1 more source
Immunology, Volume 177, Issue 2, Page 299-316, February 2026.We utilised long‐read Nanopore sequencing to characterise the transcriptome of ferret cell lines stimulated with IFN‐α as well as nasal turbinates from ferrets infected with influenza A virus. We identified novel genes and isoforms and observed elongation of poly(A) tails in the ribosome and Coronavirus Disease‐19 pathways in response to IFN‐α ...
Rubaiyea Farrukee +7 more
wiley +1 more source
Endothelial MLKL Inhibition Reduces Hyperoxia‐Induced Bronchopulmonary Dysplasia in Neonatal Mice
Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.ABSTRACT Bronchopulmonary dysplasia (BPD) remains a severe complication in premature infants requiring prolonged oxygen therapy, with vascular endothelial dysfunction recognised as a critical contributor to disease progression. Mixed lineage kinase domain‐like protein (MLKL)‐mediated necroptosis, an essential form of regulated cell death implicated in ...
Junjie Ning +3 more
wiley +1 more source
Bee products as alternatives in the treatment of viral infections
Journal of the Science of Food and Agriculture, Volume 106, Issue 1, Page 33-54, 15 January 2026.Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba +3 more
wiley +1 more source
Oral USC-093, a novel homoserinamide analogue of the tyrosinamide (S)-HPMPA prodrug USC-087 has decreased nephrotoxicity while maintaining antiviral efficacy against human adenovirus infection of Syrian hamsters. [PDF]
Antiviral ResTollefson AE +8 more
europepmc +1 more source
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Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde
During childhood several adenovirus infections have to be experienced, each with another of the multiple types. The spectrum of associated diseases ranges from endemic, mild and self-limiting upper respiratory tract infections to epidemic gastroenteritis, eye infections, cystitis and less frequently atypical pneumonia and severe infections of internal ...
+6 more sources
During childhood several adenovirus infections have to be experienced, each with another of the multiple types. The spectrum of associated diseases ranges from endemic, mild and self-limiting upper respiratory tract infections to epidemic gastroenteritis, eye infections, cystitis and less frequently atypical pneumonia and severe infections of internal ...
+6 more sources