Results 281 to 290 of about 236,653 (360)

Dopamine-Derived Oxidative Stress in Attention-Deficit/Hyperactivity Disorder: A Narrative Review of Molecular Mechanisms, Neural Circuitry, and Therapeutic Implications. [PDF]

Antioxidants (Basel)
Țocu G, Ștefănescu BI, Țocu L, Dimofte F, Luțenco V, Stavăr Matei L, Dănilă MD, Marin MC, Matei MN, Mihailov OM, Iacobescu P, Mihailov R.   +11 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Validation of a criterion-based screening and triage pathway for adult ADHD: a prospective observational study of safety and operational efficiency. [PDF]

Front Psychiatry
Adamou M, Fullen T, Crisp R, Hallett E, Spencer L, Wharton L, Jones SL.   +6 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Synergistic and redundant information dynamics exhibit dissociable alterations across schizophrenia and neurodevelopmental conditions. [PDF]

Brain Inform
Nago H, Kojima H, Yamaguchi H, Yamashita Y.   +3 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Pain in Children With ADHD: Mechanisms, Clinical Presentation, and Implications for Assessment and Management. [PDF]

In Vivo
Muzio MR, Vittori A, Capitello TG, Esposito D, Bruno MP, Cerrone V, Cascella M.   +6 more
europepmc   +1 more source

Association between problematic smartphone use and ADHD symptoms among nursing students at a Saudi public university. [PDF]

Front Psychiatry
Sharif L, Baeshen J, Abuhabaya K, Alsadik D, Alwagdani H, Elsayes H, Alatawi AOA, El-Ashry AM.   +7 more
europepmc   +1 more source

Relating ADHD to the aperiodic component of the EEG signal in both males and females across development. [PDF]

Dev Cogn Neurosci
Panda EJ, Arulnandhy S, Tekok-Kilic A, Segalowitz SJ, Marshall W.   +4 more
europepmc   +1 more source

Neurodevelopmental disorders and the gut microbiome: insights into ADHD and tic disorders. [PDF]

Front Microbiol
Li J, Qiu X.
europepmc   +1 more source